In order to examine whether intratracheal instillation studies can be useful for determining
the harmful effect of nanoparticles, we performed inhalation and intratracheal instillation …

We conducted inhalation and intratracheal instillation studies of zinc oxide (ZnO) nanoparticles
in order to examine their pulmonary toxicity. F344 rats were received intratracheal …

Inhalation studies are the gold standard for the estimation of the harmful effects of respirable
chemical substances, while there is limited evidence of the harmful effects of chemical …

We performed inhalation and intratracheal instillation studies of cerium dioxide (CeO 2 )
nanoparticles in order to investigate their pulmonary toxicity, and observed pulmonary …

The proliferation and differentiation properties of embryoid bodies (EB) from mouse embryonic
stem (ES) cells were compared under two microchip conditions: microwell chip and …

In order to investigate the pulmonary toxicity of titanium dioxide (TiO 2 ) nanoparticles, we
performed an intratracheal instillation study with rats of well-dispersed TiO 2 nanoparticles and …

The hazards of various types of nanoparticles with high functionality have not been fully
assessed. We investigated the usefulness of biopersistence as a hazard indicator of …

The formation of three-dimensional cell microspheres such as spheroids, embryoid bodies,
and neurospheres has attracted attention as a useful culture technique. In this study, we …

Objectives We performed the two inhalation exposures, whole-body inhalation and nose-only
inhalation, to investigate the pulmonary deposition and health effects of the two inhalation …

NiO nanoparticles were administered to rat lungs via intratracheal instillation or inhalation.
During pulmonary toxicity caused by NiO nanoparticles, the induction of oxidative stress is a …