Feasibility of discontinuing biologics in severe asthma: an algorithmic approach

K Hamada, K Oishi, Y Murata, T Hirano… - Journal of Asthma and …, 2021 - Taylor & Francis
In severe asthma with type 2 (T2) inflammation, biologics targeting key mediators of T2
inflammation, including interleukin (IL)-5, IL-4/IL-13, and immunoglobulin (Ig)E, remarkably …

Association between cytokine removal by polymyxin B hemoperfusion and improved pulmonary oxygenation in patients with acute exacerbation of idiopathic …

…, T Miyasho, K Aoe, Y Ogata, H Katayama, Y Murata… - Cytokine, 2013 - Elsevier
Acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) is characterized by severe
worsening dyspnea of unknown etiology and high mortality without effective treatment. Recently, …

[HTML][HTML] A real-world study of achievement rate and predictive factors of clinical and deep remission to biologics in patients with severe asthma

K Oishi, K Hamada, Y Murata, K Matsuda… - Journal of Clinical …, 2023 - mdpi.com
Background: Recent advances in biologics have provided new insights into the clinical course
of asthma, including disease modification, clinical remission (CR), and deep remission (…

[HTML][HTML] Pleural effusion related to IgG4

Y Murata, K Aoe, Y Mimura - Current Opinion in Pulmonary …, 2019 - journals.lww.com
Murata, Yoriyuki a,b ; Aoe, Keisuke a,b ; Mimura, Yusuke a … Murata et al. [29▪] reported
that 12 of 35 (34%) patients with pleural effusions undiagnosed during follow-up (median, 5 …

Impact of sinus surgery on type 2 airway and systemic inflammation in asthma

…, S Uehara, R Suetake, S Ohata, Y Murata… - Journal of …, 2021 - Taylor & Francis
Objective: Asthma is frequently associated with chronic rhinosinusitis with nasal polyps (CRSwNP).
Although endoscopic sinus surgery (ESS) improves asthma control in CRSwNP …

Survival from an acute exacerbation of idiopathic pulmonary fibrosis with or without direct hemoperfusion with a polymyxin B-immobilized fiber column: a retrospective …

K Oishi, K Aoe, Y Mimura, Y Murata, K Sakamoto… - Internal …, 2016 - jstage.jst.go.jp
Objective Acute exacerbations of idiopathic pulmonary fibrosis (AE-IPF) are fatal episodes
of acute respiratory worsening of unknown etiology. Previous studies on acute respiratory …

[HTML][HTML] The 1-minute sit-to-stand test to detect desaturation during 6-minute walk test in interstitial lung disease

…, S Uehara, R Suetake, S Ohata, Y Murata… - NPJ primary care …, 2022 - nature.com
Although the 6 min walk test (6MWT) is well-established for assessing desaturation in patients
with interstitial lung disease (ILD), it cannot be easily performed in primary healthcare …

Detection of type2 biomarkers for response in COPD

…, K Matsuda, R Suetake, Y Murata… - Journal of Breath …, 2020 - iopscience.iop.org
Chronic obstructive pulmonary disease (COPD) is a heterogeneous inflammatory lung disease.
It is important to identify patients who would respond to anti-inflammatory treatment. This …

[HTML][HTML] A novel role of growth differentiation factor (GDF)-15 in overlap with sedentary lifestyle and cognitive risk in COPD

…, S Uehara, K Hamada, S Ohata, Y Murata… - Journal of clinical …, 2020 - mdpi.com
Sedentary behavior and cognitive impairment have a direct impact on patients’ outcomes.
An energy metabolic disorder may be involved in the overlap of these comorbid conditions (…

[HTML][HTML] Utility of the Shortness of Breath in Daily Activities Questionnaire (SOBDA-Q) to Detect Sedentary Behavior in Patients with Chronic Obstructive Pulmonary …

…, K Hamada, S Ohata, R Suetake, Y Murata… - Journal of Clinical …, 2023 - mdpi.com
Sedentary behavior has been shown to be an independent predictor of mortality in patients
with chronic obstructive pulmonary disease (COPD). However, physicians have difficulty …