A 3-D conjugated bond-pair-based peridynamic model is developed to comprehensively
investigate failure characteristics of rock-like materials with intermittent fissures in the …

The therapeutic effect of arsenic trioxide (As 2 O 3 ) in the treatment of acute promyelocytic
leukemia (APL) was evaluated among 15 APL patients at relapse after all-trans retinoic acid (…

Activation of N-methyl-d-aspartate subtype glutamate receptors (NMDARs) is required for
long-term potentiation (LTP) and long-term depression (LTD) of excitatory synaptic …

An important part of a distributed system design is the choice of a load sharing or global
scheduling strategy. A comprehensive literature survey on this topic is presented. We propose a …

Long-term potentiation and long-term depression are processes that have been widely
studied to understand the molecular basis of information storage in the brain. Glutamate …

Excitotoxicity, the specific type of neurotoxicity mediated by glutamate, may be the missing
link between ischemia and neuronal death, and intervening the mechanistic steps that lead to …

Long-term depression (LTD) in the CNS has been the subject of intense investigation as a
process that may be involved in learning and memory and in various pathological conditions. …

N-methyl-d-aspartate receptors (NMDARs) mediate ischemic brain damage but also mediate
essential neuronal excitation. To treat stroke without blocking NMDARs, we transduced …

Long-term potentiation (LTP) of excitatory transmission in the hippocampus likely contributes
to learning and memory. The mechanisms underlying LTP at these synapses are not well …

Well-documented experimental evidence from both in vitro and in vivo models of stroke
strongly supports the critical involvement of NMDA receptor-mediated excitotoxicity in neuronal …