… Cytotoxic γδ T cells expressed a stronger adherence and higher cytotoxicity towards endothelial
cells, higher levels of pro-inflammatory cytokines such as TNFα and interleukin-8 (IL-8), …

Chronic obstructive pulmonary disease (COPD) is a leading cause of death and disability
internationally. Alveolar hypoxia and consequent hypoxemia increase in prevalence as …

The diagnosis of obstructive sleep apnea syndrome (OSAS) requires the combined
assessment of relevant clinical features and the objective demonstration of abnormal breathing …

Background— Obstructive sleep apnea syndrome (OSAS), characterized by intermittent
hypoxia/reoxygenation (IHR), is an independent risk factor for cardiovascular disease. We …

Background Obstructive sleep apnea syndrome (OSAS) has been associated with increased
morbidity and mortality, principally from cardiovascular disease, but the impact of nasal …

Background: Circulating nuclear factor-κB (NF-κB)–dependent genes, particularly tumor
necrosis factor-α (TNF-α), are elevated in obstructive sleep apnea syndrome (OSAS) and likely …

The possible role of high nasal airway resistance in the pathogenesis of obstructive sleep
apnea has been examined in 7 patients with seasonal (ragweed) allergic rhinitis, a naturally …

Chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea syndrome
represent two of the most prevalent chronic respiratory disorders in clinical practice, and …

The publication of “The Sleep Apnea Syndromes” by Guilleminault et al. in the 1970s
hallmarked the discovery of a new disease entity involving serious health consequences. …

Conclusions Grading the strength of recommendations and the quality of underlying evidence
enhances the usefulness of clinical practice guidelines. Professional societies and other …