El establecimiento del sexo en mamíferos ocurre al momento de la fertilización, sin embargo,
se requiere de la determinación y diferenciación sexual de la gónada para que se …

El cáncer epitelial de ovario (CEO) representa la tercera neoplasia ginecológica más frecuente
a nivel mundial con 225,500 casos nuevos y 140,200 muertes en 2008, 1 de éstas, 50% …

Temperature sex determining species offer a model for investigating how environmental
cues become integrated to the regulation of patterning genes and growth, among bipotential …

Asthma symptoms have been associated with sex steroids. During childhood, this illness
seems more frequent in boys than in girls and this tendency reverts in puberty when it is more …

Androgens in asthmatic men may be linked to asthma severity, acting via nongenomic and
genomic effects. This ailment affects boys more than girls during infancy, and this proportion …

Theophylline is a drug commonly used to treat asthma due to its anti-inflammatory and
bronchodilatory properties. Testosterone (TES) has been suggested to reduce the severity of …

The autosomal Sry-related gene, Sox9, encodes a transcription factor, which performs an
important role in testis differentiation in mammals. In several reptiles, Sox9 is differentially …

The discovery in mammals that fetal testes are required in order to develop the male
phenotype inspired research efforts to elucidate the mechanisms underlying gonadal sex …

Hawksbill turtles are considered Critically Endangered. An understanding of how nest
microenvironment (moisture and temperature) and maternal characteristics can influence …

In turtles undergoing temperature sex determination (TSD), bipotential gonads express
Sox9 in medullary cords at both female- (FPT) and male-producing temperatures (MPT). …