Human blood monocytes are able to form extracellular traps

V Granger, D Faille, V Marani, B Noël… - Journal of leukocyte …, 2017 - academic.oup.com
Neutrophil extracellular traps (NETs) are extracellular DNA filaments formed during
neutrophil activation. This process, called netosis, was originally associated with neutrophil …

An IgG-induced neutrophil activation pathway contributes to human drug-induced anaphylaxis

F Jönsson, L de Chaisemartin, V Granger… - Science translational …, 2019 - science.org
Anaphylaxis is a systemic acute hypersensitivity reaction that is considered to depend on
allergen-specific immunoglobulin E (IgE) antibodies and histamine release by mast cells and …

Neutrophil extracellular traps are elevated in patients with pneumonia-related acute respiratory distress syndrome

I Bendib, L de Chaisemartin, V Granger… - …, 2019 - pubs.asahq.org
Editor’s Perspective What We Already Know about This Topic Neutrophil extracellular traps
are increasingly recognized as pathogenic in acute injury, but their role in sepsis-related …

[HTML][HTML] Neutrophil extracellular traps in autoimmunity and allergy: immune complexes at work

V Granger, M Peyneau, S Chollet-Martin… - Frontiers in …, 2019 - frontiersin.org
Neutrophil extracellular traps (NETs) have been initially described as main actors in host
defense owing to their ability to immobilize and sometimes kill microorganisms. Subsequent …

[HTML][HTML] Innate immune deficiencies are associated with severity and poor prognosis in patients with COVID-19

M Peyneau, V Granger, PH Wicky, D Khelifi-Touhami… - Scientific reports, 2022 - nature.com
COVID-19 can cause acute respiratory distress syndrome, leading to death in many individuals.
Evidence of a deleterious role of the innate immune system is accumulating, but the …

Blood eosinophil cationic protein and eosinophil-derived neurotoxin are associated with different asthma expression and evolution in adults

V Granger, F Zerimech, J Arab, V Siroux, P De Nadai… - Thorax, 2022 - thorax.bmj.com
Background Eosinophil-derived neurotoxin (EDN) and eosinophil cationic protein (ECP) are
proteins released by activated eosinophils whose role in adult asthma remains unclear. …

[HTML][HTML] Biomarkers for the risk of thrombosis in pancreatic adenocarcinoma are related to cancer process

…, E de Raucourt, L de Chaisemartin, V Granger… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Background Venous thrombo-embolic events (VTE) frequently occur in patients with
pancreatic ductal adenocarcinoma (PDAC) and contribute to high morbidity and mortality. …

[HTML][HTML] Circulating neutrophil and eosinophil extracellular traps are markers of severe asthma

V Granger, C Taillé, D Roach… - World Allergy …, 2020 - worldallergyorganizationjournal.org
Background Neutrophil and eosinophil extracellular traps (NETs and EETs) are web-like
structures with anti-infectious and pro-inflammatory properties whose involvement in the …

[HTML][HTML] Differential activation of human neutrophils by SARS-CoV-2 variants of concern

…, A David, HR Chenane, V Granger… - Frontiers in …, 2022 - frontiersin.org
The emerging SARS-CoV-2 virus has affected the entire world with over 600 million confirmed
cases and 6.5 million deaths as of September 2022. Since the beginning of the pandemic, …

[HTML][HTML] Nrf2 downregulates zymosan-induced neutrophil activation and modulates migration

DG Helou, S Braham, L De Chaisemartin, V Granger… - PLoS …, 2019 - journals.plos.org
Polymorphonuclear neutrophils (PMNs) are the first line of defense against pathogens and
their activation needs to be tightly regulated in order to limit deleterious effects. Nrf2 (Nuclear …