Recent studies have recognised the importance of pulmonary hypertension (PH) in sickle
cell disease (SCD). The aim of this study was to determine the prevalence and prognostic …

Isolated non-compaction cardiomyopathy is a rare disease that is likely to develop in the
embryonic period. It is caused by the intrauterine arrest of the myocardial compaction process in …

Background— Very few studies have measured disease penetrance and prognostic factors
of Chagas cardiomyopathy among asymptomatic Trypanosoma cruzi–infected persons. …

Increase in oxidative/nitrosative stress is one of the mechanisms associated with the development
of cardiotoxicity due to doxorubicin (Dox), a potent chemotherapy drug. Previously, we …

Background— Endocardial fibrous tissue (FT) deposition is a hallmark of endomyocardial
fibrosis (EMF). Echocardiography is a first-line and the standard technique for the diagnosis of …

Background Accumulated evidence shows that the ACE-AngII-AT1 axis of the renin-angiotensin
system (RAS) is markedly activated in chronic heart failure (CHF). Recent studies …

Introduction: Heart failure with reduced ejection fraction (HFrEF) is associated with a worse
outcome. Heart rate (HR) is related to outcome in HFrEF. Ivabradine selectively inhibits I f (…

Aims Exposure to a high glucose medium or diabetes has been found to protect the heart
against ischaemia. The activation of antiapoptotic and proliferative factors seems to be …

Background Blood donor screening leads to large numbers of new diagnoses of Trypanosoma
cruzi infection, with most donors in the asymptomatic chronic indeterminate form. …

Background: COVID-19 has become a dramatic health problem during this century. In
addition to high mortality rate, COVID-19 survivors are at increased risk for cardiovascular …