Interplay between microRNAs and the epigenetic machinery: an intricate network
microRNAs take their place into the epigenetic world revealing a complicated network of
reciprocal interconnections: not only they are able to control gene expression at a post-…
reciprocal interconnections: not only they are able to control gene expression at a post-…
Breast cancer and microRNAs: therapeutic impact
Despite advances in detection and therapies, breast cancer is still the leading cause of cancer
death in women worldwide. The etiology of this neoplasm is complex, and both genetic …
death in women worldwide. The etiology of this neoplasm is complex, and both genetic …
[HTML][HTML] Aberrant signaling pathways in T-cell acute lymphoblastic leukemia
D Bongiovanni, V Saccomani, E Piovan - International journal of …, 2017 - mdpi.com
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive disease caused by the malignant
transformation of immature progenitors primed towards T-cell development. Clinically, T-…
transformation of immature progenitors primed towards T-cell development. Clinically, T-…
microRNA-205 regulates HER3 in human breast cancer
MV Iorio, P Casalini, C Piovan, G Di Leva, A Merlo… - Cancer research, 2009 - AACR
An increasing amount of experimental evidence shows that microRNAs can have a causal
role in breast cancer tumorigenesis as a novel class of oncogenes or tumor suppressor genes…
role in breast cancer tumorigenesis as a novel class of oncogenes or tumor suppressor genes…
MicroRNA cluster 221-222 and estrogen receptor α interactions in breast cancer
G Di Leva, P Gasparini, C Piovan… - JNCI: Journal of the …, 2010 - academic.oup.com
Background Several lines of evidence have suggested that estrogen receptor α (ERα)–negative
breast tumors, which are highly aggressive and nonresponsive to hormonal therapy, …
breast tumors, which are highly aggressive and nonresponsive to hormonal therapy, …
[PDF][PDF] Direct reversal of glucocorticoid resistance by AKT inhibition in acute lymphoblastic leukemia
Glucocorticoid resistance is a major driver of therapeutic failure in T cell acute lymphoblastic
leukemia (T-ALL). Here, we identify the AKT1 kinase as a major negative regulator of the …
leukemia (T-ALL). Here, we identify the AKT1 kinase as a major negative regulator of the …
BCL6 suppression of BCL2 via Miz1 and its disruption in diffuse large B cell lymphoma
M Saito, U Novak, E Piovan, K Basso… - Proceedings of the …, 2009 - National Acad Sciences
The BCL6 proto-oncogene encodes a transcriptional repressor that is required for germinal
center (GC) formation and whose deregulation by genomic lesions is implicated in the …
center (GC) formation and whose deregulation by genomic lesions is implicated in the …
The ITER full size plasma source device design
…, S Peruzzo, A Pesce, N Pilan, R Piovan… - Fusion Engineering and …, 2009 - Elsevier
In the framework of the strategy for the development and the procurement of the NB systems
for ITER, it has been decided to build in Padova a test facility, including two experimental …
for ITER, it has been decided to build in Padova a test facility, including two experimental …
[HTML][HTML] Oncosuppressive role of p53-induced miR-205 in triple negative breast cancer
C Piovan, D Palmieri, G Di Leva, L Braccioli… - Molecular …, 2012 - Elsevier
An increasing body of evidence highlights an intriguing interaction between microRNAs and
transcriptional factors involved in determining cell fate, including the well known “genome …
transcriptional factors involved in determining cell fate, including the well known “genome …
[HTML][HTML] Estrogen mediated-activation of miR-191/425 cluster modulates tumorigenicity of breast cancer cells depending on estrogen receptor status
G Di Leva, C Piovan, P Gasparini, A Ngankeu… - PLoS …, 2013 - journals.plos.org
MicroRNAs (miRNAs), single-stranded non-coding RNAs, influence myriad biological
processes that can contribute to cancer. Although tumor-suppressive and oncogenic functions …
processes that can contribute to cancer. Although tumor-suppressive and oncogenic functions …