Atherosclerosis is associated with alterations in nitric oxide (NO)/cGMP signaling. In early
stages of the disease, inflammatory and possibly other cells produce reactive oxygen species …

We analysed the influence of rhinovirus (RV) in nasopharyngeal fluid (NPF) on type I and III
interferon (IFN) responses (eg IFN-α and IFN-λ) and their signal transduction, at baseline …

Background X-linked hypohidrotic ectodermal dysplasia (XLHED) is caused by pathogenic
variants of the gene EDA disrupting the prenatal development of ectodermal derivatives. …

The endothelium-derived relaxing factors nitric oxide (NO) and prostacyclin (PGI 2 ) are
important antithrombotic, relaxant, and antiproliferative agents of the blood vessel wall that exert …

Here we investigated the relationship between local bacterial colonization and anti-bacterial
immune responses in pre-school asthmatic and control children within the EU-wide study …

The proinflammatory cytokine interleukin-17A (IL-17A) is known to mediate antimicrobial
activity, but its role during rhinovirus (RV) infections and in asthma needs further investigation. …

Background/Aims: In cystic fibrosis (CF), chronic microbial lung infections are difficult to treat
and cause morbidity and increased mortality. Methods: In a multicentre, open-label, …

To the Editor: Nuclear factor of activated T cells (NFAT) is a family of transcription factors
activated by dephosphorylation mediated by Ca 11-activated calcineurin. NFAT coordinates …

Background In individuals with cystic fibrosis (CF), colonization with methicillin-resistant
Staphylococcus aureus (MRSA) was reported to be associated with a deterioration of pulmonary …

LETTERS TO THE EDITOR 283 rhinovirus expressed increased levels of TGFBRII compared
with the respective controls (Fig 2, C). This finding suggests that rhinovirus induced TGF-b …