Endothelial cell protein C receptor: a multiliganded and multifunctional receptor
…, CT Esmon, UR Pendurthi - Blood, The Journal of …, 2014 - ashpublications.org
Endothelial cell protein C receptor (EPCR) was first identified and isolated as a cellular
receptor for protein C on endothelial cells. EPCR plays a crucial role in the protein C …
receptor for protein C on endothelial cells. EPCR plays a crucial role in the protein C …
Tissue factor–factor VIIa signaling
LVM Rao, UR Pendurthi - Arteriosclerosis, thrombosis, and …, 2005 - Am Heart Assoc
How does tissue factor (TF), whose principle role is to support clotting factor VIIa (FVIIa) in
triggering the coagulation cascade, affect various pathophysiological processes? One of the …
triggering the coagulation cascade, affect various pathophysiological processes? One of the …
[HTML][HTML] Regulation of tissue factor coagulant activity on cell surfaces
LVM Rao, UR Pendurthi - Journal of thrombosis and haemostasis, 2012 - Elsevier
Tissue factor (TF) is a transmembrane glycoprotein and an essential component of the factor
VIIa‐TF enzymatic complex that triggers activation of the coagulation cascade. Formation of …
VIIa‐TF enzymatic complex that triggers activation of the coagulation cascade. Formation of …
Tissue factor-factor VIIa–specific up-regulation of IL-8 expression in MDA-MB-231 cells is mediated by PAR-2 and results in increased cell migration
…, BB Sorensen, PL Norby, SK Mandal, UR Pendurthi… - Blood, 2004 - ashpublications.org
… , including our own, shows that the TF-FVIIa complex, independent of other downstream
proteases, activates typical G-protein–coupled receptor pathways (for a review, see Pendurthi …
proteases, activates typical G-protein–coupled receptor pathways (for a review, see Pendurthi …
Resveratrol, a polyphenolic compound found in wine, inhibits tissue factor expression in vascular cells: a possible mechanism for the cardiovascular benefits …
UR Pendurthi, JT Williams, LVM Rao - … , thrombosis, and vascular …, 1999 - Am Heart Assoc
A number of studies suggest that moderate consumption of red wine may be more effective
than other alcoholic beverages in decreasing the risk of coronary heart disease mortality. The …
than other alcoholic beverages in decreasing the risk of coronary heart disease mortality. The …
[HTML][HTML] Endothelial cell protein C receptor acts as a cellular receptor for factor VIIa on endothelium
S Ghosh, UR Pendurthi, A Steinoe, CT Esmon… - Journal of biological …, 2007 - ASBMB
Although factor VII/factor VIIa (FVII/FVIIa) is known to interact with many non-vascular cells,
activated monocytes, and endothelial cells via its binding to tissue factor (TF), the interaction …
activated monocytes, and endothelial cells via its binding to tissue factor (TF), the interaction …
[HTML][HTML] Vascular endothelial growth factor (VEGF)-induced up-regulation of CCN1 in osteoblasts mediates proangiogenic activities in endothelial cells and promotes …
…, V Alt, UR Pendurthi, UM Liegibel, U Sommer… - Journal of Biological …, 2007 - ASBMB
Angiogenesis is indispensable during fracture repair, and vascular endothelial growth factor
(VEGF) is critical in this process. CCN1 (CYR61) is an extracellular matrix signaling …
(VEGF) is critical in this process. CCN1 (CYR61) is an extracellular matrix signaling …
Inhibition of tissue factor gene activation in cultured endothelial cells by curcumin: suppression of activation of transcription factors Egr-1, AP-1, and NF-κB
UR Pendurthi, JT Williams, LVM Rao - … , thrombosis, and vascular …, 1997 - Am Heart Assoc
… – 9200 (to Dr Pendurthi) from The University of Texas Health Center at Tyler. Dr Pendurthi
… Idell (HL-45018 from NHLBI), The University of Texas Health Center at Tyler. During this …
… Idell (HL-45018 from NHLBI), The University of Texas Health Center at Tyler. During this …
Cellular localization and trafficking of tissue factor
SK Mandal, UR Pendurthi, LVM Rao - Blood, 2006 - ashpublications.org
Tissue factor (TF) is the cellular receptor for clotting factor VIIa (FVIIa). The formation of TF-FVIIa
complexes on cell surfaces triggers the activation of coagulation cascade and cell …
complexes on cell surfaces triggers the activation of coagulation cascade and cell …
Factor VIIa bound to endothelial cell protein C receptor activates protease activated receptor-1 and mediates cell signaling and barrier protection
…, CA Clark, CT Esmon, UR Pendurthi… - Blood, The Journal …, 2011 - ashpublications.org
Recent studies have shown that factor VIIa (FVIIa) binds to the endothelial cell protein C
receptor (EPCR), a cellular receptor for protein C and activated protein C, but the physiologic …
receptor (EPCR), a cellular receptor for protein C and activated protein C, but the physiologic …