Genome-wide association study identifies five loci associated with lung function

…, PH Whincup, GD Smith, S Ebrahim, TM McKeever… - Nature …, 2010 - nature.com
Pulmonary function measures are heritable traits that predict morbidity and mortality and
define chronic obstructive pulmonary disease (COPD). We tested genome-wide association …

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function

…, F Kronenberg, JZ Liu, J Marchini, T McKeever… - Nature …, 2011 - nature.com
Pulmonary function measures reflect respiratory health and are used in the diagnosis of
chronic obstructive pulmonary disease. We tested genome-wide association with forced …

Prenatal and passive smoke exposure and incidence of asthma and wheeze: systematic review and meta-analysis

…, Y Chen, DG Cook, JR Britton, TM McKeever - …, 2012 - publications.aap.org
OBJECTIVES: Exposure to passive smoke is a common and avoidable risk factor for wheeze
and asthma in children. Substantial growth in the prospective cohort study evidence base …

Global incidence and mortality of idiopathic pulmonary fibrosis: a systematic review

…, A Fogarty, R Hubbard, T McKeever - European Respiratory …, 2015 - Eur Respiratory Soc
As idiopathic pulmonary fibrosis emerges as an important public health problem, there is a
need to coordinate data on incidence and mortality globally. This study aims to systematically …

In-hospital mortality after surgical lung biopsy for interstitial lung disease in the United States. 2000 to 2011

JP Hutchinson, AW Fogarty, TM McKeever… - American journal of …, 2016 - atsjournals.org
Rationale: Surgical lung biopsy can help to determine a specific diagnosis in interstitial lung
disease but has associated risks. Most currently available mortality data are derived from …

[HTML][HTML] Parental and household smoking and the increased risk of bronchitis, bronchiolitis and other lower respiratory infections in infancy: systematic review and …

LL Jones, A Hashim, T McKeever, DG Cook… - Respiratory …, 2011 - Springer
Background Passive smoke exposure increases the risk of lower respiratory infection (LRI)
in infants, but the extensive literature on this association has not been systematically …

Early exposure to infections and antibiotics and the incidence of allergic disease: a birth cohort study with the West Midlands General Practice Research Database

TM McKeever, SA Lewis, C Smith, J Collins… - Journal of Allergy and …, 2002 - Elsevier
Background: It has been suggested that the rise in prevalence of allergic disease in westernized
countries is due in part to a decrease in exposure to infections and an increase in the …

The importance of prenatal exposures on the development of allergic disease: a birth cohort study using the West Midlands General Practice Database

TM McKeever, SA Lewis, C Smith… - American journal of …, 2002 - atsjournals.org
The etiology of allergic disease is not understood, but a decreased exposure to infection may
play an important role. There are few published data on the impact of change in microbial …

[HTML][HTML] Longitudinal change in collagen degradation biomarkers in idiopathic pulmonary fibrosis: an analysis from the prospective, multicentre PROFILE study

…, PL Molyneaux, TM McKeever… - The lancet Respiratory …, 2015 - thelancet.com
Background Idiopathic pulmonary fibrosis, a progressive and inevitably fatal disorder, has a
highly variable clinical course. Biomarkers that reflect disease activity are urgently needed to …

[HTML][HTML] Co-infection in critically ill patients with COVID-19: an observational cohort study from England

…, ML Schmid, TM McKeever… - Journal of medical …, 2021 - microbiologyresearch.org
Introduction. During previous viral pandemics, reported co-infection rates and implicated
pathogens have varied. In the 1918 influenza pandemic, a large proportion of severe illness …