User profiles for Thomas Dieterle

Thomas Dieterle, MD, MHBA, Professor of Cardiology

University of Basel
Verified email at unibas.ch
Cited by 2790

Tolerability, safety, pharmacokinetics, and efficacy of doxorubicin-loaded anti-EGFR immunoliposomes in advanced solid tumours: a phase 1 dose-escalation study

…, R Ritschard, A Wicki, G Stehle, T Dieterle… - The lancet …, 2012 - thelancet.com
Background Results of preclinical studies have shown that EGFR immunoliposomes have
substantial antitumour effects. We aimed to assess the tolerability, safety, pharmokinetics, and …

[HTML][HTML] The value of in vitro diagnostic testing in medical practice: a status report

UP Rohr, C Binder, T Dieterle, F Giusti, CGM Messina… - PloS one, 2016 - journals.plos.org
Background In vitro diagnostic (IVD) investigations are indispensable for routine patient
management. Appropriate testing allows early-stage interventions, reducing late-stage …

[HTML][HTML] Chronic phospholamban inhibition prevents progressive cardiac dysfunction and pathological remodeling after infarction in rats

…, Y Gu, M Iwatate, T Dieterle… - The Journal of …, 2004 - Am Soc Clin Investig
Ablation or inhibition of phospholamban (PLN) has favorable effects in several genetic murine
dilated cardiomyopathies, and we showed previously that a pseudophosphorylated form …

Myeloid differentiation factor-88/interleukin-1 signaling controls cardiac fibrosis and heart failure progression in inflammatory dilated cardiomyopathy

P Blyszczuk, G Kania, T Dieterle, RR Marty… - Circulation …, 2009 - Am Heart Assoc
Rationale: The myeloid differentiation factor (MyD)88/interleukin (IL)-1 axis activates self–antigen-presenting
cells and promotes autoreactive CD4 + T-cell expansion in experimental …

[HTML][HTML] Use and inhalation technique of inhaled medication in patients with asthma and COPD: data from a randomized controlled trial

C Gregoriano, T Dieterle, AL Breitenstein, S Dürr… - Respiratory …, 2018 - Springer
Background The burden of asthma and COPD among patients is high and people affected
are frequently hospitalized due to exacerbations. There are numerous reasons for the lack of …

Relation between insufficient response to antihypertensive treatment and poor compliance with treatment: a prospective case-control study

R Nuesch, K Schroeder, T Dieterle, B Martina… - Bmj, 2001 - bmj.com
Objectives: To prospectively compare compliance with treatment in patients with hypertension
responsive to treatment versus patients with treatment resistant hypertension. Design: …

Incidence, clinical predictors, and prognostic impact of worsening renal function in elderly patients with chronic heart failure on intensive medical therapy

…, T Fehr, D Hack, D Weilenmann, T Dieterle… - American heart …, 2012 - Elsevier
BACKGROUND: Incidence, predictors, and prognostic impact of worsening renal function (WRF)
in elderly patients with chronic heart failure (HF) undergoing intensive contemporary …

Ionic impurity in a Bose-Einstein condensate at submicrokelvin temperatures

KS Kleinbach, F Engel, T Dieterle, R Löw, T Pfau… - Physical review …, 2018 - APS
Rydberg atoms immersed in a Bose-Einstein condensate interact with the quantum gas via
electron-atom and ion-atom interaction. To suppress the typically dominant electron-neutral …

Specific inhibition of fibroblast activation protein (FAP)-alpha prevents tumor progression in vitro

…, K Chaitanya, R Boger, K Gordon, T Dieterle… - Advances in medical …, 2015 - Elsevier
Purpose Solid tumors modulate their environment to keep non-malignant stromal cells in a
tumor-promoting state. The main cells in the stroma of epithelial derived tumors are cancer …

Observation of Rydberg blockade induced by a single ion

F Engel, T Dieterle, T Schmid, C Tomschitz, C Veit… - Physical Review Letters, 2018 - APS
We study the long-range interaction of a single ion with a highly excited ultracold Rydberg
atom and report on the direct observation of an ion-induced Rydberg excitation blockade …