User profiles for Takahiro Nakajima

Takahiro Nakajima

獨協医科大学、呼吸器外科学
Verified email at med.miyazaki-u.ac.jp
Cited by 9236

The utility of sonographic features during endobronchial ultrasound-guided transbronchial needle aspiration for lymph node staging in patients with lung cancer: a …

T Fujiwara, K Yasufuku, T Nakajima, M Chiyo… - Chest, 2010 - Elsevier
Background Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA)
is a minimally invasive procedure with a high yield for lymph node staging of lung cancer. …

Assessment of epidermal growth factor receptor mutation by endobronchial ultrasound-guided transbronchial needle aspiration

T Nakajima, K Yasufuku, M Suzuki, K Hiroshima… - Chest, 2007 - Elsevier
Background The presence of somatic mutations in epidermal growth factor receptor (EGFR)
predicts the effectiveness of EGFR tyrosine kinase inhibitors (TKIs). It would be ideal if an …

Endobronchial ultrasound: new insight for the diagnosis of sarcoidosis

M Wong, K Yasufuku, T Nakajima… - European …, 2007 - Eur Respiratory Soc
A diagnosis of sarcoidosis should be substantiated by pathological means in order to
thoroughly exclude other diseases. The role of real-time endobronchial ultrasound-guided …

[HTML][HTML] EML4-ALK mutations in lung cancer that confer resistance to ALK inhibitors

…, T Ueno, J Takashima, T Nakajima… - … England Journal of …, 2010 - Mass Medical Soc
<p id="p001">The EML4 (echinoderm microtubule-associated protein-like 4)–ALK (anaplastic
lymphoma kinase) fusion-type tyrosine kinase is an oncoprotein found in 4 to 5% of non–…

[HTML][HTML] The role of EBUS-TBNA for the diagnosis of sarcoidosis–comparisons with other bronchoscopic diagnostic modalities

T Nakajima, K Yasufuku, K Kurosu, Y Takiguchi… - Respiratory …, 2009 - Elsevier
BACKGROUND: The diagnosis of sarcoidosis requires both compatible clinical features
and pathologic findings as a means to exclude other differential diagnoses. The utility of …

Photoactivatable CRISPR-Cas9 for optogenetic genome editing

Y Nihongaki, F Kawano, T Nakajima, M Sato - Nature biotechnology, 2015 - nature.com
We describe an engineered photoactivatable Cas9 (paCas9) that enables optogenetic control
of CRISPR-Cas9 genome editing in human cells. paCas9 consists of split Cas9 fragments …

Comparison of endobronchial ultrasound, positron emission tomography, and CT for lymph node staging of lung cancer

K Yasufuku, T Nakajima, K Motoori, Y Sekine… - Chest, 2006 - Elsevier
Study objectives To perform a prospective comparison of direct real-time endobronchial
ultrasound (EBUS)-guided transbronchial needle aspiration (TBNA), positron emission …

Significant increase of serum high-mobility group box chromosomal protein 1 levels in patients with severe acute pancreatitis

…, Y Takeyama, M Shinzeki, H Sawa, T Nakajima… - Pancreas, 2006 - journals.lww.com
Objective: Multiple organ failure because of systemic inflammatory response in the early
phase and sepsis in the late phase is the main contributor to high mortality in severe acute …

Guideline for the acquisition and preparation of conventional and endobronchial ultrasound-guided transbronchial needle aspiration specimens for the diagnosis and …

…, R Trisolini, DP Steinfort, B Hwangbo, T Nakajima… - Respiration, 2014 - karger.com
Rationale: Conventional transbronchial needle aspiration (TBNA) and endobronchial
ultrasound (EBUS)-TBNA are widely accepted tools for the diagnosis and staging of lung cancer …

EML4-ALK Fusion Gene Assessment Using Metastatic Lymph Node Samples Obtained by Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration

Y Sakairi, T Nakajima, K Yasufuku, D Ikebe… - Clinical Cancer …, 2010 - AACR
Purpose: Anaplastic lymphoma kinase (ALK) fusion genes represent novel oncogenes for
non–small cell lung cancers (NSCLC). Several ALK inhibitors have been developed, and are …