[HTML][HTML] Febuxostat therapy for patients with stage 3 CKD and asymptomatic hyperuricemia: a randomized trial

…, M Inaba, H Makino, S Maruyama, S Ito… - American Journal of …, 2018 - Elsevier
Rationale & Objective Epidemiologic and clinical studies have suggested that urate-lowering
therapy may slow the progression of chronic kidney disease (CKD). However, definitive …

[HTML][HTML] Interleukin-6 regulation of transforming growth factor (TGF)-β receptor compartmentalization and turnover enhances TGF-β1 signaling

XL Zhang, N Topley, T Ito, A Phillips - Journal of Biological Chemistry, 2005 - ASBMB
Transforming growth factor (TGF)-β1 is a key cytokine involved in the pathogenesis of
fibrosis in many organs, whereas interleukin (IL)-6 plays an important role in the regulation of …

First detection of koi herpesvirus in cultured common carp Cyprinus carpio in Japan

M Sano, T Ito, J Kurita, T Yanai, N Watanabe… - Fish …, 2004 - jstage.jst.go.jp
Mass mortality among common carp Cyprinus carpio, especially in large-sized fish cultured
in Lake Kasumigaura, has occurred since early October 2003. The affected fish swam …

Long-term exposure of proximal tubular epithelial cells to glucose induces transforming growth factor-β1 synthesis via an autocrine PDGF loop

D Fraser, N Brunskill, T Ito, A Phillips - The American journal of pathology, 2003 - Elsevier
We have recently reported increased transforming growth factor (TGF)-β1 gene transcription
in proximal tubular cells within 12 hours of exposure to 25 mmol/L d-glucose, with a …

Endoscopic tissue shielding method with polyglycolic acid sheets and fibrin glue to cover wounds after colorectal endoscopic submucosal dissection (with video)

…, M Shozushima, J Hamanaka, A Ohno, T Ito… - Gastrointestinal …, 2014 - Elsevier
Background Colorectal endoscopic submucosal dissection (ESD) has made it possible to
resect large specimens in an en bloc fashion. However, this can lead to postoperative adverse …

[HTML][HTML] Angiotensin II induces fibronectin expression in human peritoneal mesothelial cells via ERK1/2 and p38 MAPK

K Kiribayashi, T Masaki, T Naito, T Ogawa, T Ito… - Kidney international, 2005 - Elsevier
… Author links open overlay panel Kei Kiribayashi , Takao Masaki , Takayuki Naito ,
Takahiko Ogawa , Takafumi Ito , Noriaki Yorioka , Nobuoki Kohno …

[HTML][HTML] Risk factors for bleeding after endoscopic submucosal dissection for gastric lesions

Y Tsuji, K Ohata, T Ito, H Chiba, T Ohya… - World journal of …, 2010 - ncbi.nlm.nih.gov
AIM: To assess risk factors for bleeding after gastric endoscopic submucosal dissection (ESD)
and to develop preventive measures. METHODS: This retrospective study was performed …

[HTML][HTML] Hyaluronan regulates transforming growth factor-β1 receptor compartmentalization

T Ito, JD Williams, DJ Fraser, AO Phillips - Journal of Biological Chemistry, 2004 - ASBMB
Transforming growth factor-β1 (TGF-β1) is a key cytokine involved in the pathogenesis of
fibrosis in many organs. We previously demonstrated in renal proximal tubular cells that the …

Kidney outcomes associated with SGLT2 inhibitors versus other glucose-lowering drugs in real-world clinical practice: the Japan chronic kidney disease database

…, Y Terada, T Shigematsu, T Sofue, T Ito… - Diabetes …, 2021 - Am Diabetes Assoc
OBJECTIVE Randomized controlled trials have shown kidney-protective effects of sodium–glucose
cotransporter 2 (SGLT2) inhibitors, and clinical practice databases have suggested …

Renal disease in the elderly and the very elderly Japanese: analysis of the Japan Renal Biopsy Registry (J-RBR)

…, A Shimizu, K Oka, N Nakagawa, T Ito… - Clinical and …, 2012 - Springer
Background and objectives Data regarding renal disease in the elderly (age ≥65 years old)
and very elderly (age ≥80 years old) Japanese are extremely limited. The aim of this study …