[HTML][HTML] Biomarkers for acute respiratory distress syndrome and prospects for personalised medicine

…, M Park, C Turrini, T Tunstall, R Thwaites, T Mauri… - Journal of …, 2019 - Springer
Acute lung injury (ALI) affects over 10% of patients hospitalised in critical care, with acute
respiratory distress syndrome (ARDS) being the most severe form of ALI and having a mortality …

Dynamics of an emerging disease drive large-scale amphibian population extinctions

…, RA Knapp, TS Tunstall… - Proceedings of the …, 2010 - National Acad Sciences
… ) of three categories of frog populations: (i) populations before detection of Bd (r t for each …
In each case, r t = ln(N t ) − ln(N t −1 ), where N t is the number of adult frogs in the lake in year t

Population genetics of the frog-killing fungus Batrachochytrium dendrobatidis

…, RA Knapp, MJ Stice, T Tunstall… - Proceedings of the …, 2007 - National Acad Sciences
Global amphibian decline by chytridiomycosis is a major environmental disaster that has been
attributed to either recent fungal spread or environmental change that promotes disease. …

[HTML][HTML] Markers of endothelial and epithelial pulmonary injury in mechanically ventilated COVID-19 ICU patients

…, G Campo, O Zucchetti, M Verri, I Ottaviani, T Tunstall… - Critical care, 2021 - Springer
… The variables normally distributed were compared by t test; otherwise the Mann–Whitney
U was used. Categorical variables were summarized in terms of numbers and percentages …

Neutrophilic inflammation in the respiratory mucosa predisposes to RSV infection

…, A Varese, A Owen, L Cuthbertson, P James, T Tunstall… - Science, 2020 - science.org
INTRODUCTION Even with intimate exposure to a virus, some people fail to become infected.
Variable transmission partly depends on the dose and duration of exposure but is also …

[HTML][HTML] A comprehensive evaluation of nasal and bronchial cytokines and chemokines following experimental rhinovirus infection in allergic asthma: increased …

TT Hansel, T Tunstall, MB Trujillo-Torralbo, B Shamji… - …, 2017 - thelancet.com
Background Rhinovirus infection is a major cause of asthma exacerbations. Objectives We
studied nasal and bronchial mucosal inflammatory responses during experimental rhinovirus-…

More than skin deep: functional genomic basis for resistance to amphibian chytridiomycosis

AR Ellison, T Tunstall, GV DiRenzo… - Genome biology and …, 2015 - academic.oup.com
… species exhibited suppression of splenic T-cell genes. We … due in part to their ability to mount
T-cell–mediated responses to … limited only to T cells, but include a deeper inhibition of T cell …

[HTML][HTML] Whole-genome risk prediction of common diseases in human preimplantation embryos

A Kumar, K Im, M Banjevic, PC Ng, T Tunstall… - Nature medicine, 2022 - nature.com
Preimplantation genetic testing (PGT) of in-vitro-fertilized embryos has been proposed as a
method to reduce transmission of common disease; however, more comprehensive embryo …

Reduced nasal viral load and IFN responses in infants with respiratory syncytial virus bronchiolitis and respiratory failure

…, C Feather, F Abdulla, T Tunstall… - American journal of …, 2018 - atsjournals.org
Rationale: Respiratory syncytial virus (RSV) bronchiolitis is a major cause of morbidity and
mortality in infancy. Severe disease is believed to result from uncontrolled viral replication, an …

[HTML][HTML] Is chytridiomycosis an emerging infectious disease in Asia?

…, M Stöck, BL Stuart, LS Torres, DTA Tran, TS Tunstall… - PloS one, 2011 - journals.plos.org
The disease chytridiomycosis, caused by the fungus Batrachochytrium dendrobatidis (Bd),
has caused dramatic amphibian population declines and extinctions in Australia, Central and …