AACR Project GENIE: powering precision medicine through an international consortium

…, JC Soria, P Sripakdeevong, NH Stickle, TP Stricker… - Cancer discovery, 2017 - AACR
The AACR Project GENIE is an international data-sharing consortium focused on generating
an evidence base for precision cancer medicine by integrating clinical-grade cancer …

Integrative and comparative genomic analysis of HPV-positive and HPV-negative head and neck squamous cell carcinomas

…, MK Keck, A Khattri, CS Pedamallu, T Stricker… - Clinical cancer …, 2015 - AACR
Purpose: The genetic differences between human papilloma virus (HPV)–positive and –negative
head and neck squamous cell carcinomas (HNSCC) remain largely unknown. To …

Establishing a consortium for the study of rare diseases: The Urea Cycle Disorders Consortium

…, ML Oster-Granite, MR Seashore, T Stricker… - Molecular genetics and …, 2010 - Elsevier
The Urea Cycle Disorders Consortium (UCDC) was created as part of a larger network
established by the National Institutes of Health to study rare diseases. This paper reviews the …

Integrative analysis of head and neck cancer identifies two biologically distinct HPV and three non-HPV subtypes

MK Keck, Z Zuo, A Khattri, TP Stricker, CD Brown… - Clinical cancer …, 2015 - AACR
Purpose: Current classification of head and neck squamous cell carcinomas (HNSCC) based
on anatomic site and stage fails to capture biologic heterogeneity or adequately inform …

No further increase in asthma, hay fever and atopic sensitisation in adolescents living in Switzerland

…, K Takken-Sahli, U Neu, T Stricker… - European …, 2004 - Eur Respiratory Soc
Prevalence rates of childhood asthma and allergy have been on the increase for several
decades. The present study investigated whether this trend continued during the 1990s in …

Vulvovaginitis in prepubertal girls

T Stricker, F Navratil, FH Sennhauser - Archives of Disease in …, 2003 - adc.bmj.com
This retrospective study evaluated the clinical features and findings in bacterial cultures and
in microscopic examination of vaginal secretions in 80 prepubertal girls, aged 2–12 years, …

Molecular profiling of cancer—the future of personalized cancer medicine: a primer on cancer biology and the tools necessary to bring molecular testing to the clinic

T Stricker, DVT Catenacci, TY Seiwert - Seminars in oncology, 2011 - Elsevier
… Author links open overlay panel Thomas Stricker a b , Daniel VT Catenacci c d , Tanguy Y. …
, cigarette smoke has been shown to massively increase the number of G to T transversions. …

[HTML][HTML] Pro-collagenase-1 (matrix metalloproteinase-1) binds the α2β1 integrin upon release from keratinocytes migrating on type I collagen

JA Dumin, SK Dickeson, TP Stricker… - Journal of Biological …, 2001 - ASBMB
… Indeed, pro-MMP-2 also interacts with MMP-14 and TIMP-2 (tissue inhibitor ofmetalloproteinase
2) on the cell surface, and this trimeric complex is essential for activation of this …

CUX1 is a haploinsufficient tumor suppressor gene on chromosome 7 frequently inactivated in acute myeloid leukemia

…, S Yu, J Ko, BP Sandall, T Stricker… - Blood, The Journal …, 2013 - ashpublications.org
Loss of chromosome 7 and del(7q) [−7/del(7q)] are recurring cytogenetic abnormalities in
hematologic malignancies, including acute myeloid leukemia and therapy-related myeloid …

Trends in prevalence of asthma, allergic rhinitis and atopic dermatitis in 5–7‐year old Swiss children from 1992 to 2001

…, K Takken‐Sahli, FH Sennhauser, T Stricker… - Allergy, 2006 - Wiley Online Library
Background: Changing occurrence rates of asthma, allergic rhinitis and atopic dermatitis
are of public health concern and require surveillance. Changes in prevalence rates of these …