User profiles for T. Oni

Tolu Oni

- Verified email at uct.ac.za - Cited by 7933

Tobiloba Oni

- Verified email at cshl.edu - Cited by 5250

Tina Toni

- Verified email at mit.edu - Cited by 3292

[HTML][HTML] The Lancet Nigeria Commission: investing in health and the future of the nation

…, S Obaro, A Yinka-Ogunleye, F Okonofua, T Oni… - The Lancet, 2022 - thelancet.com
Health is central to the development of any country. Nigeria's gross domestic product is the
largest in Africa, but its per capita income of about₦ 770 000 (US $2000) is low with a highly …

Understanding the rise of cardiometabolic diseases in low-and middle-income countries

…, C Corvalan, AA Hyder, M Lazo-Porras, T Oni… - Nature medicine, 2019 - nature.com
Increases in the prevalence of noncommunicable diseases (NCDs), particularly cardiometabolic
diseases such as cardiovascular disease, stroke and diabetes, and their major risk …

Managing membrane stress: the phage shock protein (Psp) response, from molecular mechanisms to physiology

…, C Engl, G Jovanovic, M Huvet, T Toni… - FEMS microbiology …, 2010 - academic.oup.com
The bacterial phage shock protein (Psp) response functions to help cells manage the impacts
of agents impairing cell membrane function. The system has relevance to biotechnology …

Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer

…, M Ponz-Sarvise, V Corbo, TE Oni… - Journal of Experimental …, 2017 - rupress.org
Pancreatic stellate cells (PSCs) differentiate into cancer-associated fibroblasts (CAFs) that
produce desmoplastic stroma, thereby modulating disease progression and therapeutic …

An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis

…, CM Graham, FW McNab, Z Xu, SAA Bloch, T Oni… - Nature, 2010 - nature.com
… Percentages of B cells, and of T cells carrying the … T cells carrying the CD4 antigen (Fig.
3b and Supplementary Fig. 9a, b), in keeping with previous studies 15 . That the reduction in T-…

[PDF][PDF] Organoid models of human and mouse ductal pancreatic cancer

…, H Tiriac, MS Spector, A Gracanin, T Oni… - Cell, 2015 - cell.com
Pancreatic cancer is one of the most lethal malignancies due to its late diagnosis and limited
response to treatment. Tractable methods to identify and interrogate pathways involved in …

IL1-induced JAK/STAT signaling is antagonized by TGFβ to shape CAF heterogeneity in pancreatic ductal adenocarcinoma

G Biffi, TE Oni, B Spielman, Y Hao, E Elyada, Y Park… - Cancer discovery, 2019 - AACR
… G, qPCR analysis of Il1a, Il6, Lif, Cxcl1, Csf3, Acta2, and Ctgf in LIF knockout PSCs compared
with Rosa26-targeted controls cultured in Matrigel in transwell with tumor organoids (T orgs…

[HTML][HTML] Slum health: arresting COVID-19 and improving well-being in urban informal settlements

…, J Weru, S Ouma, K Edmundo, T Oni… - Journal of urban …, 2020 - Springer
The informal settlements of the Global South are the least prepared for the pandemic of
COVID-19 since basic needs such as water, toilets, sewers, drainage, waste collection, and …

Approximate Bayesian computation scheme for parameter inference and model selection in dynamical systems

T Toni, D Welch, N Strelkowa… - Journal of the …, 2009 - royalsocietypublishing.org
… Here, we choose the perturbation kernel K t to be a random walk (uniform or Gaussian). …
at time t (t=2, …, T), η t , is defined as the perturbed intermediate distribution at time t−1, π t−1 , …

[HTML][HTML] Detection of tuberculosis in HIV-infected and-uninfected African adults using whole blood RNA expression signatures: a case-control study

M Kaforou, VJ Wright, T Oni, N French… - PLoS …, 2013 - journals.plos.org
Background A major impediment to tuberculosis control in Africa is the difficulty in diagnosing
active tuberculosis (TB), particularly in the context of HIV infection. We hypothesized that a …