[HTML][HTML] The Lancet Nigeria Commission: investing in health and the future of the nation
…, S Obaro, A Yinka-Ogunleye, F Okonofua, T Oni… - The Lancet, 2022 - thelancet.com
Health is central to the development of any country. Nigeria's gross domestic product is the
largest in Africa, but its per capita income of about₦ 770 000 (US $2000) is low with a highly …
largest in Africa, but its per capita income of about₦ 770 000 (US $2000) is low with a highly …
Understanding the rise of cardiometabolic diseases in low-and middle-income countries
…, C Corvalan, AA Hyder, M Lazo-Porras, T Oni… - Nature medicine, 2019 - nature.com
Increases in the prevalence of noncommunicable diseases (NCDs), particularly cardiometabolic
diseases such as cardiovascular disease, stroke and diabetes, and their major risk …
diseases such as cardiovascular disease, stroke and diabetes, and their major risk …
Managing membrane stress: the phage shock protein (Psp) response, from molecular mechanisms to physiology
The bacterial phage shock protein (Psp) response functions to help cells manage the impacts
of agents impairing cell membrane function. The system has relevance to biotechnology …
of agents impairing cell membrane function. The system has relevance to biotechnology …
Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer
Pancreatic stellate cells (PSCs) differentiate into cancer-associated fibroblasts (CAFs) that
produce desmoplastic stroma, thereby modulating disease progression and therapeutic …
produce desmoplastic stroma, thereby modulating disease progression and therapeutic …
An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis
…, CM Graham, FW McNab, Z Xu, SAA Bloch, T Oni… - Nature, 2010 - nature.com
… Percentages of B cells, and of T cells carrying the … T cells carrying the CD4 antigen (Fig.
3b and Supplementary Fig. 9a, b), in keeping with previous studies 15 . That the reduction in T-…
3b and Supplementary Fig. 9a, b), in keeping with previous studies 15 . That the reduction in T-…
[PDF][PDF] Organoid models of human and mouse ductal pancreatic cancer
Pancreatic cancer is one of the most lethal malignancies due to its late diagnosis and limited
response to treatment. Tractable methods to identify and interrogate pathways involved in …
response to treatment. Tractable methods to identify and interrogate pathways involved in …
IL1-induced JAK/STAT signaling is antagonized by TGFβ to shape CAF heterogeneity in pancreatic ductal adenocarcinoma
… G, qPCR analysis of Il1a, Il6, Lif, Cxcl1, Csf3, Acta2, and Ctgf in LIF knockout PSCs compared
with Rosa26-targeted controls cultured in Matrigel in transwell with tumor organoids (T orgs…
with Rosa26-targeted controls cultured in Matrigel in transwell with tumor organoids (T orgs…
[HTML][HTML] Slum health: arresting COVID-19 and improving well-being in urban informal settlements
The informal settlements of the Global South are the least prepared for the pandemic of
COVID-19 since basic needs such as water, toilets, sewers, drainage, waste collection, and …
COVID-19 since basic needs such as water, toilets, sewers, drainage, waste collection, and …
Approximate Bayesian computation scheme for parameter inference and model selection in dynamical systems
… Here, we choose the perturbation kernel K t to be a random walk (uniform or Gaussian). …
at time t (t=2, …, T), η t , is defined as the perturbed intermediate distribution at time t−1, π t−1 , …
at time t (t=2, …, T), η t , is defined as the perturbed intermediate distribution at time t−1, π t−1 , …
[HTML][HTML] Detection of tuberculosis in HIV-infected and-uninfected African adults using whole blood RNA expression signatures: a case-control study
Background A major impediment to tuberculosis control in Africa is the difficulty in diagnosing
active tuberculosis (TB), particularly in the context of HIV infection. We hypothesized that a …
active tuberculosis (TB), particularly in the context of HIV infection. We hypothesized that a …