User profiles for T. Lahm

Tim Lahm

Indiana University
Verified email at iu.edu
Cited by 16869

Assessment of right ventricular function in the research setting: knowledge gaps and pathways forward. An Official American Thoracic Society Research Statement

T Lahm, IS Douglas, SL Archer, HJ Bogaard… - American journal of …, 2018 - atsjournals.org
Background: Right ventricular (RV) adaptation to acute and chronic pulmonary hypertensive
syndromes is a significant determinant of short- and long-term outcomes. Although …

Medical and surgical treatment of acute right ventricular failure

T Lahm, CA McCaslin, TC Wozniak… - Journal of the American …, 2010 - jacc.org
… Hyperventilation can be used to lower PAP acutely, but should not be performed at the
expense of a high V T . Because increases in respiratory rate can cause dynamic hyperinflation …

Diagnostic workup, etiologies and management of acute right ventricle failure: a state-of-the-art paper

…, HJ Bogaard, TM Bull, N Fletcher, T Lahm… - Intensive care …, 2018 - Springer
… Recent advances: panels r–t. r Speckle tracking echocardiography, s 3D echo volumetric
analysis, t apical dyskinesia by magnetic resonance imaging (MRI) due to pulmonary …

Human mesenchymal stem cells stimulated by TNF-α, LPS, or hypoxia produce growth factors by an NFκB-but not JNK-dependent mechanism

…, Y Wang, TA Markel, M Wang, T Lahm… - … of Physiology-Cell …, 2008 - journals.physiology.org
Understanding the mechanisms by which adult stem cells produce growth factors may
represent an important way to optimize their beneficial paracrine and autocrine effects. …

Association of borderline pulmonary hypertension with mortality and hospitalization in a large patient cohort: insights from the veterans affairs clinical assessment …

…, RJ Tedford, T Lahm, KE Joynt, DJ Kass, T Stephens… - Circulation, 2016 - Am Heart Assoc
Background— Pulmonary hypertension (PH) is associated with increased morbidity across
the cardiopulmonary disease spectrum. Based primarily on expert consensus opinion, PH is …

Statement on pregnancy in pulmonary hypertension from the Pulmonary Vascular Research Institute

…, IR Preston, MR MacLean, T Lahm - Pulmonary …, 2015 - journals.sagepub.com
… Consequentially, nonspecific ST and T wave changes can be seen on an electrocardiogram.
This is accompanied by mild dilation and stretching of all cardiac chambers, as well as mild …

17β-Estradiol attenuates hypoxic pulmonary hypertension via estrogen receptor–mediated effects

T Lahm, M Albrecht, AJ Fisher, M Selej… - American journal of …, 2012 - atsjournals.org
Rationale: 17β-Estradiol (E2) attenuates hypoxic pulmonary vasoconstriction and hypoxic
pulmonary hypertension (HPH) through an unknown mechanism that may involve estrogen …

VEGF is critical for stem cell-mediated cardioprotection and a crucial paracrine factor for defining the age threshold in adult and neonatal stem cell function

…, CM Herring, J Tan, T Lahm… - American Journal …, 2008 - journals.physiology.org
Bone marrow mesenchymal stem cells (MSCs) may be a novel treatment modality for organ
ischemia, possibly through the release of beneficial paracrine factors. However, an age …

[HTML][HTML] Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis

…, DG Kiely, J Klinger, G Kovacs, T Lahm… - The lancet respiratory …, 2019 - thelancet.com
… survival from diagnosis in patients with pulmonary arterial hypertension with the C/C
homozygous genotype was double (13·50 years [95% CI 12·07 to >13·50]) that of those with the T/T

Progress in solving the sex hormone paradox in pulmonary hypertension

T Lahm, RM Tuder, I Petrache - American Journal of …, 2014 - journals.physiology.org
… The role of ERβ in PAH has not been studied in detail; exploratory studies in our laboratory
found ERβ more abundant in pulmonary arteries from PAH patients than ERα (T. Lahm, …