[HTML][HTML] Guidelines for preclinical and early phase clinical assessment of novel radiosensitisers
KJ Harrington, LJ Billingham, TB Brunner… - British journal of …, 2011 - nature.com
There is a growing appreciation of the potential value of combining novel molecularly-targeted
drugs with radiotherapy or chemoradiotherapy. Such approaches have the potential to …
drugs with radiotherapy or chemoradiotherapy. Such approaches have the potential to …
Fas ligand-induced apoptosis as a mechanism of immune privilege
… of infiltrating T cells, we placed isolated anterior segments from the eyes of uninfected mice
into culture and inoculated them with LI2l0 or LIllO-Fas cells [murine T cell lymphoma cells …
into culture and inoculated them with LI2l0 or LIllO-Fas cells [murine T cell lymphoma cells …
Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis
…, A Ziemiecki, T Schaffner, L Scapozza, T Brunner… - Nature cell …, 2006 - nature.com
Autophagy-related gene (Atg) 5 is a gene product required for the formation of autophagosomes.
Here, we report that Atg5, in addition to the promotion of autophagy, enhances …
Here, we report that Atg5, in addition to the promotion of autophagy, enhances …
In vitro cytotoxicity of oxide nanoparticles: comparison to asbestos, silica, and the effect of particle solubility
TJ Brunner, P Wick, P Manser, P Spohn… - … science & technology, 2006 - ACS Publications
Early indicators for nanoparticle-derived adverse health effects should provide a relative
measure for cytotoxicity of nanomaterials in comparison to existing toxicological data. We have …
measure for cytotoxicity of nanomaterials in comparison to existing toxicological data. We have …
[PDF][PDF] High-resolution comparative modeling with RosettaCM
We describe an improved method for comparative modeling, RosettaCM, which optimizes a
physically realistic all-atom energy function over the conformational space defined by …
physically realistic all-atom energy function over the conformational space defined by …
Search for Neutrinoless Double-Beta Decay in with EXO-200
We report on a search for neutrinoless double-beta decay of Xe 136 with EXO-200. No signal
is observed for an exposure of 32.5 kg yr, with a background of∼ 1.5× 10− 3 kg− 1 yr− 1 …
is observed for an exposure of 32.5 kg yr, with a background of∼ 1.5× 10− 3 kg− 1 yr− 1 …
RANTES and macrophage inflammatory protein 1 alpha induce the migration and activation of normal human eosinophil granulocytes.
… infiltrates of certain inflammatory processes found in parasitic infection or in allergic diseases
consist predominantly of eosinophilic granulocytes, often in association with activated T …
consist predominantly of eosinophilic granulocytes, often in association with activated T …
Oxide nanoparticle uptake in human lung fibroblasts: effects of particle size, agglomeration, and diffusion at low concentrations
LK Limbach, Y Li, RN Grass, TJ Brunner… - … science & technology, 2005 - ACS Publications
… In a simplified form the particle population can be given as monodisperse with a total
concentration n t (m - 3 ) and an aggregation rate constant β (m 3 s - 1 ) as well as the stability ratio …
concentration n t (m - 3 ) and an aggregation rate constant β (m 3 s - 1 ) as well as the stability ratio …
Induction of human IgE synthesis in B cells by mast cells and basophils
JF Gauchat, S Henchoz, G Mazzei, JP Aubry, T Brunner… - Nature, 1993 - nature.com
… IgE production by B cells requires a physical interaction with T cells 1 , involving a number
of surface adhesion molecules 1,2 , as well as the soluble factors interleukin-4 (IL-4) 3,4 and IL…
of surface adhesion molecules 1,2 , as well as the soluble factors interleukin-4 (IL-4) 3,4 and IL…
Chemical properties of solid biofuels—significance and impact
I Obernberger, T Brunner, G Bärnthaler - Biomass and bioenergy, 2006 - Elsevier
… Obernberger I, Dahl J, Brunner T. Formation, composition and particle size distribution of fly
… Nussbaumer T. Primary and secondary measures for the reduction of nitric oxide emissions …
… Nussbaumer T. Primary and secondary measures for the reduction of nitric oxide emissions …