Cough is one of the most common presenting symptoms of COVID-19, along with fever and
loss of taste and smell. Cough can persist for weeks or months after SARS-CoV-2 infection, …

Chronic cough is globally prevalent across all age groups. This disorder is challenging to treat
because many pulmonary and extrapulmonary conditions can present with chronic cough…

These guidelines incorporate the recent advances in chronic cough pathophysiology, diagnosis
and treatment. The concept of cough hypersensitivity has allowed an umbrella term that …

Background Gefapixant is an oral P2X 3 receptor antagonist that has previously shown efficacy
and safety in refractory chronic cough and unexplained chronic cough. We therefore aim …

… The inspiratory flow was standardised at 0·5 L/s with an inspiratory flow regulator valve.
We counted coughs for 30 s after exposure to each dose, during which the participant's rated …

Background We performed systematic reviews using the population, intervention, comparison,
outcome (PICO) format to answer the following key clinical question: Are the CHEST 2006 …

Background Unexplained chronic cough (UCC) causes significant impairments in quality of
life. Effective assessment and treatment approaches are needed for UCC. Methods This …

In 2011, a European Respiratory Society Task Force embarked on a process to determine
the position and clinical relevance of the cough hypersensitivity syndrome, a disorder …

Bronchopulmonary C-fibers and a subset of mechanically sensitive, acid-sensitive myelinated
sensory nerves play essential roles in regulating cough. These vagal sensory nerves …

Cough is a common symptom of many respiratory diseases. The evaluation of its intensity
and frequency of occurrence could provide valuable clinical information in the assessment of …