[HTML][HTML] Effects of a Peptide Derived from the Primary Sequence of a Kallikrein Inhibitor Isolated from Bauhinia bauhinioides (pep-BbKI) in an Asthma–COPD Overlap …

…, BM Saraiva-Romanholo, SKM Bezerra… - International Journal of …, 2023 - mdpi.com
(1) There are several patients with asthma–COPD overlap (ACO). A peptide derived from
the primary sequence of a kallikrein inhibitor isolated from Bauhinia bauhinioides (pep-BbKI) …

[HTML][HTML] Cold bubble humidification of low-flow oxygen does not prevent acute changes in inflammation and oxidative stress at nasal mucosa

LA Santana, SKM Bezerra, BM Saraiva-Romanholo… - Scientific Reports, 2021 - nature.com
Some clinical situations require the use of oxygen therapy for a few hours without hypoxemia.
However, there are no literature reports on the effects of acute oxygen therapy on the …

[HTML][HTML] Investigating the Effects of a New Peptide, Derived from the Enterolobium contortisiliquum Proteinase Inhibitor (EcTI), on Inflammation, Remodeling, and …

…, TM Dos Santos, HT Dos Santos, SKM Bezerra… - International Journal of …, 2023 - mdpi.com
The synthesized peptide derived from Enterolobium contortisiliquum (pep3-EcTI) has been
associated with potent anti-inflammatory and antioxidant effects, and it may be a potential …

Effects of Environmental Exposure to Iron Powder in Healthy and Elastase-Exposed Mice

…, TM dos Santos, SSS Hamaguchi, SKM Bezerra… - 2023 - researchsquare.com
Background: Prolonged exposure to iron powder and other mineral dusts can harm affected
populations, especially those with COPD. The goal of this study was to see how …

Occupational asthma and allergic asthma: differences in the physical activity level, clinical control, and airway inflammation

…, CES Galvão, SF Nogueira, SKM Bezerra… - 2023 - Eur Respiratory Soc
The physical activity level (PAL) and clinical features were poorly compared in occupational
asthma (OA) with allergic asthma (AA). Aim: To compare the PAL, clinical control, and …

Glycine efficacy for prevention or treatment on LPS-acute lung injury in mice

…, LDN Camargo, BM Saraiva-Romanholo, SKM Bezerra… - 2021 - Eur Respiratory Soc
Glycine efficacy for prevention or trreatment on LPS-acute lung injury in mice Background:
Glycine showed an important effect on neutrophilic inflammation, involved in ALI/ARDS. Thus …

Effects of Bauhinia bauhinioides kallikrein proteinase inhibitor in mice with asthma-COPD

…, TT Galli, BM Saraiva-Romanholo, SKM Bezerra… - 2020 - Eur Respiratory Soc
Background: Asthma and chronic obstructive pulmonary disease (COPD) are major public
health problems. There is a significant proportion of patients with asthma associated with …

Treatment with proteinase inhibitor from Enterolobium contortisiliquum in mice with asthma-COPD

…, TT Galli, BM Saraiva-Romanholo, SKM Bezerra… - 2020 - Eur Respiratory Soc
Background: Patients with asthma associated with chronic obstructive pulmonary disease
presented symptoms with poor response to gold standard treatment. Proteinase inhibitor from …

Plant protease inhibitors compared to corticosteroids in mice with Asthma-COPD

…, TT Galil, BM Saraiva-Romanholo, SKM Bezerra… - 2020 - Eur Respiratory Soc
Background: Plant protease inhibitors have anti-inflammatory activities and represent
potential treatment for inflammatory diseases. Aims: To investigate the effects of Enterolobium …

Low dose of sodium hypochlorite impair lung function, inflammation and oxidative stress of naïve mice

…, GDV Lievore, FM De Almeida, SKM Bezerra… - 2019 - Eur Respiratory Soc
Background: Acute or chronic exposures to an irritant, such as sodium hypochlorite (NaClO)
can induce occupational asthma. Aim: To explore the consequences of acute and chronic …