The neurodegenerative synucleinopathies, including Parkinson’s disease and dementia
with Lewy bodies, are characterized by a typically lengthy prodromal period of progressive …

Purpose To determine if variables of the pupillary light response mature with age and sex in
a healthy pediatric cohort and the utility of pupillometry in assessment among pediatric …

Glucocorticoid (GC)-responsive epithelial–mesenchymal interactions regulate lung
development. The GC receptor (GR) mediates GC signaling. Mice lacking GR in all tissues die at …

To explore the physiological functions of endothelin-2 (ET-2), we generated gene-targeted
mouse models. Global Et2 knockout mice exhibited severe growth retardation and juvenile …

The aim of this study was to characterise lung function and bronchoalveolar lavage sphingolipid
profile in newborn mice during hyperoxia exposure and recovery in room air, and to …

Background Gait impairments are common in Parkinson's Disease (PD) and are likely
caused by degeneration in multiple brain circuits, including the basal ganglia, thalamus and …

Respiratory diseases of the newborn can arise from the disruption of essential angiogenic
pathways. Neuropilin-1 (NRP1), which is a critical receptor implicated in systemic vascular …

Background Gait impairment is a debilitating and progressive feature of Parkinson’s disease
(PD). Increasing evidence suggests that gait control is partly mediated by cholinergic …

The disruption of angiogenic pathways, whether through genetic predisposition or as a
consequence of life-saving interventions, may underlie many pulmonary diseases of infancy, …

INTRODUCTION Isolated/idiopathic rapid eye movement sleep behavior disorder (iRBD) is
a powerful early predictor of dementia with Lewy bodies (DLB) and Parkinson's disease (PD)…