User profiles for Stanley J. Szefler

Stanley Szefler

Professor of Pediatrics, University of Colorado School of Medicine
Verified email at childrenscolorado.org
Cited by 55204

An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials …

…, SW Stoloff, SD Sullivan, SJ Szefler… - American journal of …, 2009 - atsjournals.org
Background: The assessment of asthma control is pivotal to the evaluation of treatment
response in individuals and in clinical trials. Previously, asthma control, severity, and …

[HTML][HTML] Long-term inhaled corticosteroids in preschool children at high risk for asthma

…, DT Mauger, SJ Boehmer, SJ Szefler… - … England Journal of …, 2006 - Mass Medical Soc
Background It is unknown whether inhaled corticosteroids can modify the subsequent
development of asthma in preschool children at high risk for asthma. Methods We randomly …

COVID-19 and the impact of social determinants of health

EM Abrams, SJ Szefler - The Lancet Respiratory Medicine, 2020 - thelancet.com
The novel coronavirus disease 2019 (COVID-19), caused by the pathogen severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), originated in Wuhan, China, and has now …

Bronchoscopic evaluation of severe asthma: persistent inflammation associated with high dose glucocorticoids

SE Wenzel, SJ Szefler, DYM Leung… - American journal of …, 1997 - atsjournals.org
The role of inflammation in the pathogenesis of severe asthma chronically treated with high
doses of glucocorticoids is poorly understood. Despite this, treatment has been aimed at …

A summary of the new GINA strategy: a roadmap to asthma control

…, E Pizzichini, M Soto-Quiroz, SJ Szefler… - European …, 2015 - Eur Respiratory Soc
Over the past 20 years, the Global Initiative for Asthma (GINA) has regularly published and
annually updated a global strategy for asthma management and prevention that has formed …

[HTML][HTML] Randomized trial of omalizumab (anti-IgE) for asthma in inner-city children

…, A Togias, KM Thompson, SJ Szefler… - … England Journal of …, 2011 - Mass Medical Soc
Background Research has underscored the effects of exposure and sensitization to allergens
on the severity of asthma in inner-city children. It has also revealed the limitations of …

Significant variability in response to inhaled corticosteroids for persistent asthma

SJ Szefler, RJ Martin, TS King, HA Boushey… - Journal of Allergy and …, 2002 - Elsevier
Background: A clinical model is needed to compare inhaled corticosteroids (ICSs) with
respect to efficacy. Objective: The purpose of this investigation was to compare the relative …

Characterization of within-subject responses to fluticasone and montelukast in childhood asthma

SJ Szefler, BR Phillips, FD Martinez… - Journal of Allergy and …, 2005 - Elsevier
BACKGROUND: Responses to inhaled corticosteroids (ICSs) and leukotriene receptor
antagonists (LTRAs) vary among asthmatic patients. OBJECTIVE: We sought to determine …

Use of regularly scheduled albuterol treatment in asthma: genotype-stratified, randomised, placebo-controlled cross-over trial

…, SP Peters, E Silverman, CA Sorkness, SJ Szefler… - The Lancet, 2004 - thelancet.com
Background The issue of whether regular use of an inhaled β 2 -adrenergic agonist worsens
airflow and clinical outcomes in asthma is controversial. Retrospective studies have …

[HTML][HTML] Tiotropium bromide step-up therapy for adults with uncontrolled asthma

…, CA Sorkness, ER Sutherland, SJ Szefler… - … England Journal of …, 2010 - Mass Medical Soc
Background Long-acting beta-agonist (LABA) therapy improves symptoms in patients whose
asthma is poorly controlled by an inhaled glucocorticoid alone. Alternative treatments for …