Autosomal dominant deficiency of signal transducer and activator of transcription 3 (STAT3)
is the main genetic etiology of hyper-immunoglobulin (Ig) E syndrome. We documented the …

Objective To assess whether esophageal manometric motor disturbances are associated
with abnormalities consistent with interstitial lung disease (ILD) on both pulmonary function …

OBJECTIVES: The aims of the present study were to (1) assess clinical features and long-term
outcome in anti-Jo1-positive patients with anti-Ro52 antibody; (2) compare characteristics …

Background The use of cyclophosphamide in patients with acute exacerbation of idiopathic
pulmonary fibrosis (IPF) is unknown. Our study was designed to evaluate the efficacy and …

Background The natural history of pulmonary Langerhans cell histiocytosis (PLCH) has been
unclear due to the absence of prospective studies. The rate of patients who experience an …

Objective To investigate the short-term adverse events and effectiveness of lumacaftor/ivacaftor
combination treatment in adults with cystic fibrosis (CF) and severe lung disease in a …

Because Langerhans cells (LC) in peripheral tissues are generally “immature” cells with
poor lymphostimulatory activity, the contribution of immune responses initiated by LC to the …

Objective To describe the efficacy and safety of omalizumab, an anti‐IgE monoclonal antibody,
in patients with refractory and/or relapsing eosinophilic granulomatosis with polyangiitis (…

Little is known about longitudinal lung function variation in patients with pulmonary Langerhans’
cell histiocytosis (LCH). The contribution of serial lung computed tomography (CT) to …

Rationale: Systemic steroids are the standard treatment for bronchiolitis obliterans syndrome
(BOS) after allogeneic hematopoietic stem cell transplantation (HSCT) despite their poor …