Asthma is the most prevalent pediatric chronic disease and affects more than 300 million
people worldwide. Recent evidence in mice has identified a “critical window” early in life where …

Although antibiotics have significantly improved human health and life expectancy, their
disruption of the existing microbiota has been linked to significant side effects such as antibiotic-…

In this study, the effects of deleting two genes previously implicated in Haloferax volcanii N-glycosylation
on the assembly and attachment of a novel Asn-linked pentasaccharide …

The gastrointestinal (GI) microbiota is a complex community of microorganisms residing within
the mammalian gastrointestinal tract. The GI microbiota is vital to the development of the …

Intestinal helminth infections occur predominantly in regions where exposure to enteric
bacterial pathogens is also common. Helminth infections inhibit host immunity against microbial …

N-glycosylation in Archaea presents aspects of this posttranslational modification not seen
in either Eukarya or Bacteria. In the haloarchaeon Haloferax volcanii , the surface (S)-layer …

The mammalian gut contains a complex assembly of commensal microbes termed
microbiota. Although much has been learned about the role of these microbes in health, the …

Proteins in all three domains of life can experience N‐glycosylation. The steps involved in the
archaeal version of this post‐translational modification remain largely unknown. Hence, as …

The pathogenesis of Salmonella Typhimurium depends on the bacterium’s ability to survive
and replicate within host cells. The formation and maintenance of a unique membrane-…

Like Eukarya and Bacteria, Archaea are also capable of performing N‐glycosylation. In the
halophilic archaeon Haloferax volcanii, N‐glycosylation is mediated by the products of the …