[HTML][HTML] Identification of hypoxia-response element in the human endothelial nitric-oxide synthase gene promoter
F Coulet, S Nadaud, M Agrapart, F Soubrier - Journal of Biological …, 2003 - ASBMB
The human endothelial nitric-oxide synthase gene (heNOS) is constitutively expressed in
endothelial cells, and its expression is induced under hypoxia. The goal of this study was to …
endothelial cells, and its expression is induced under hypoxia. The goal of this study was to …
[HTML][HTML] Acetylation of TAFI68, a subunit of TIF‐IB/SL1, activates RNA polymerase I transcription
V Muth, S Nadaud, I Grummt, R Voit - The EMBO journal, 2001 - embopress.org
Mammalian rRNA genes are preceded by a terminator element that is recognized by the
transcription termination factor TTF‐I. In exploring the functional significance of the promoter‐…
transcription termination factor TTF‐I. In exploring the functional significance of the promoter‐…
Gene structure, polymorphism and mapping of the human endothelial nitric oxide synthase gene
S Nadaud, A Bonnardeaux, M Lathrop… - … and biophysical research …, 1994 - Elsevier
Endothelium-derived relaxing factor (EDRF)/nitric oxide (NO) is synthesized from L-Arginine
by the endothelial, constitutive, NO synthase. To facilitate genetic studies, we have cloned …
by the endothelial, constitutive, NO synthase. To facilitate genetic studies, we have cloned …
Sustained increase in aortic endothelial nitric oxide synthase expression in vivo in a model of chronic high blood flow
S Nadaud, M Philippe, JF Arnal, JB Michel… - Circulation …, 1996 - Am Heart Assoc
Physiological adaptation of normal blood vessels to acute or chronic changes in blood flow
is endothelium dependent. In vitro studies have shown that, among other genes, NO …
is endothelium dependent. In vitro studies have shown that, among other genes, NO …
[PDF][PDF] Evidence for a familial pregnancy-induced hypertension locus in the eNOS-gene region
R Arngrímsson, C Hayward, S Nadaud… - The American Journal of …, 1997 - cell.com
Pregnancy-induced hypertension may be regarded as a manifestation of endothelial-cell
dysfunction. The role of the eNOS gene in the development of a familial pregnancy-induced …
dysfunction. The role of the eNOS gene in the development of a familial pregnancy-induced …
The Wnt/beta‐catenin pathway is activated during advanced arterial aging in humans
…, C Le Feuvre, F Soubrier, AM Lompré, S Nadaud - Aging cell, 2011 - Wiley Online Library
Aging is the main risk factor for cardiovascular diseases, but the associated molecular
mechanisms are poorly understood. The Wnt signaling pathway was shown to be induced during …
mechanisms are poorly understood. The Wnt signaling pathway was shown to be induced during …
Genome-wide association analysis identifies a susceptibility locus for pulmonary arterial hypertension
…, O Poirier, B Girerd, P Dorfmüller, F Coulet, S Nadaud… - Nature …, 2013 - nature.com
Pulmonary arterial hypertension (PAH) is a rare, severe disease resulting from progressive
obliteration of small-caliber pulmonary arteries by proliferating vascular cells. PAH can occur …
obliteration of small-caliber pulmonary arteries by proliferating vascular cells. PAH can occur …
miR-424/322 regulates vascular smooth muscle cell phenotype and neointimal formation in the rat
…, N Mougenot, A Jacquet, S Nadaud… - Cardiovascular …, 2013 - academic.oup.com
Aims Our aim was to identify new microRNAs (miRNAs) implicated in pathological vascular
smooth muscle cells (VSMCs) proliferation and characterize their mechanism of action. …
smooth muscle cells (VSMCs) proliferation and characterize their mechanism of action. …
Genetic analyses in a cohort of children with pulmonary hypertension
…, I Szezepanski, M Ladouceur, S Nadaud… - European …, 2016 - Eur Respiratory Soc
The prevalence of germline mutations in paediatric pulmonary hypertension (PH) is poorly
documented. The objective of this study was to determine the mutation frequency in PH genes …
documented. The objective of this study was to determine the mutation frequency in PH genes …
Circulating and cellular markers of endothelial dysfunction with aging in rats
M Challah, S Nadaud, M Philippe… - American Journal …, 1997 - journals.physiology.org
The influence of age on endothelial functional markers was investigated in rats. Angiotensin
I converting enzyme (ACE) activity and nitric oxide synthase (NOS) mRNA expressions were …
I converting enzyme (ACE) activity and nitric oxide synthase (NOS) mRNA expressions were …