User profiles for Sofia Lundin
Sofia LundinRIA iMed, AstraZeneca Verified email at astrazeneca.com Cited by 196 |
[HTML][HTML] The beneficial effects of n-3 polyunsaturated fatty acids on diet induced obesity and impaired glucose control do not require Gpr120
M Bjursell, X Xu, T Admyre, G Böttcher, S Lundin… - PloS one, 2014 - journals.plos.org
GPR120 (Ffar4) has been postulated to represent an important receptor mediating the improved
metabolic profile seen upon ingestion of a diet enriched in polyunsaturated fatty acids (…
metabolic profile seen upon ingestion of a diet enriched in polyunsaturated fatty acids (…
Multi-omics links IL-6 trans-signalling with neutrophil extracellular trap formation and Haemophilus infection in COPD
…, H Lindmark, A Wellner, S Lundin… - European …, 2021 - Eur Respiratory Soc
Background: Interleukin (IL)-6 trans-signalling (IL-6TS) is emerging as a pathogenic mechanism
in chronic respiratory diseases; however, the drivers of IL-6TS in the airways and the …
in chronic respiratory diseases; however, the drivers of IL-6TS in the airways and the …
The development of AZD7624 for prevention of exacerbations in COPD: a randomized controlled trial
…, S Asimus, T Hegelund-Myrbäck, S Lundin… - … journal of chronic …, 2018 - Taylor & Francis
Background p38 mitogen-activated protein kinase (MAPK) plays a central role in the regulation
and activation of pro-inflammatory mediators. COPD patients have increased levels of …
and activation of pro-inflammatory mediators. COPD patients have increased levels of …
Role of secretory phospholipases in atherogenesis
AC Jönsson-Rylander, S Lundin, B Rosengren… - Current atherosclerosis …, 2008 - Springer
Elevated circulating levels of secretory phospholipase A 2 (sPLA 2 ) are associated with
atherosclerotic cardiovascular disease. sPLA 2 can contribute to atherogenesis by hydrolyzing …
atherosclerotic cardiovascular disease. sPLA 2 can contribute to atherogenesis by hydrolyzing …
AZD7624, an Inhaled p38 Inhibitor, Demonstrates Local Lung Inhibition of LPS-Induced TNFα with Minimal Systemic Exposure
Inhaled drugs generally aim to drive a local pharmacological effect in lung, at the same time
minimizing systemic exposure, in order to obtain efficacy in lung disease without unwanted …
minimizing systemic exposure, in order to obtain efficacy in lung disease without unwanted …
A randomized controlled trial of AZD7624, an inhaled p38 MAP kinase inhibitor, in COPD patients on ICS/LABA with a history of frequent exacerbations
…, MN Brown, M Fageras, S Lundin… - … COPD ADVANCES IN …, 2017 - atsjournals.org
Prior study has shown that p38 MAP kinase (MAPK) is upregulated in alveolar macrophages
in patients with COPD, and p38 activation increases with COPD severity. We hypothesized …
in patients with COPD, and p38 activation increases with COPD severity. We hypothesized …
AZD7624, an inhaled p38 inhibitor for COPD, attenuates lung and systemic inflammation after LPS Challenge in humans
Inhaled LPS Challenge has been used to test compounds for COPD. Systemic markers of
inflammation, (eg neutrophil count, IL-6 levels, and CRP), are associated with risk of acute …
inflammation, (eg neutrophil count, IL-6 levels, and CRP), are associated with risk of acute …
Åldersdiskriminering:-är den svenska arbetsrätten åldersdiskriminerande?
S Lundin - 2012 - diva-portal.org
Since several rules of law have a consideration of age, the Swedish labor law collides in
many ways with the prohibition of age discrimination. The employment directives of EU were …
many ways with the prohibition of age discrimination. The employment directives of EU were …
Lokalitet, globalitet och folklighet: Hälsingegårdarna som världsarv
S Lundin - 2015 - diva-portal.org
The aim of this essay was to investigate the effects of adopting a site to the UNESCOs World
Heritage List. The focus laid on the example of the Decorated Farmhouses of Hälsingland, …
Heritage List. The focus laid on the example of the Decorated Farmhouses of Hälsingland, …
Late Breaking Abstract-The inflammasome cluster is linked with airway NETosis in COPD
Introduction and aim: Emerging evidence suggests that NLR pyrin domain-containing protein
3 (NLRP3) inflammasome activation may be persistent in the airways and contribute to …
3 (NLRP3) inflammasome activation may be persistent in the airways and contribute to …