T-bet and Eomes instruct the development of two distinct natural killer cell lineages in the liver and in the bone marrow
…, K Yoh, S Takahashi, I Prinz, S de Bernard… - Journal of Experimental …, 2014 - rupress.org
Trail + DX5 − Eomes − natural killer (NK) cells arise in the mouse fetal liver and persist in
the adult liver. Their relationships with Trail − DX5 + NK cells remain controversial. We …
the adult liver. Their relationships with Trail − DX5 + NK cells remain controversial. We …
Terminal NK cell maturation is controlled by concerted actions of T-bet and Zeb2 and is essential for melanoma rejection
…, A Conidi, J Chaix, P Mangeot, S de Bernard… - Journal of experimental …, 2015 - rupress.org
Natural killer (NK) cell maturation is a tightly controlled process that endows NK cells with
functional competence and the capacity to recognize target cells. Here, we found that the …
functional competence and the capacity to recognize target cells. Here, we found that the …
A novel genomic signature with translational significance for human idiopathic pulmonary fibrosis
Y Bauer, J Tedrow, S de Bernard… - American journal of …, 2015 - atsjournals.org
The bleomycin-induced rodent lung fibrosis model is commonly used to study mechanisms
of lung fibrosis and to test potential therapeutic interventions, despite the well recognized …
of lung fibrosis and to test potential therapeutic interventions, despite the well recognized …
MMP-7 is a predictive biomarker of disease progression in patients with idiopathic pulmonary fibrosis
Y Bauer, ES White, S de Bernard… - ERJ open …, 2017 - Eur Respiratory Soc
Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease with poor
prognosis, which is characterised by destruction of normal lung architecture and excessive …
prognosis, which is characterised by destruction of normal lung architecture and excessive …
[HTML][HTML] Mature IgM-expressing plasma cells sense antigen and develop competence for cytokine production upon antigenic challenge
…, L Barthly, F Jagot, S This, S De Bernard… - Nature …, 2016 - nature.com
Dogma holds that plasma cells, as opposed to B cells, cannot bind antigen because they have
switched from expression of membrane-bound immunoglobulins (Ig) that constitute the B-…
switched from expression of membrane-bound immunoglobulins (Ig) that constitute the B-…
[HTML][HTML] Identifying early pulmonary arterial hypertension biomarkers in systemic sclerosis: machine learning on proteomics from the DETECT cohort
Y Bauer, S de Bernard, P Hickey… - European …, 2021 - Eur Respiratory Soc
Pulmonary arterial hypertension (PAH) is a devastating complication of systemic sclerosis (SSc).
Screening for PAH in SSc has increased detection, allowed early treatment for PAH and …
Screening for PAH in SSc has increased detection, allowed early treatment for PAH and …
Cell surface protein disulfide-isomerase is involved in the shedding of human thyrotropin receptor ectodomain
J Couet, S de Bernard, H Loosfelt, B Saunier… - Biochemistry, 1996 - ACS Publications
In human thyroid glands the TSH receptor undergoes a cleavage reaction which yields to
an extracellular α subunit and a membrane spanning β subunit linked together by disulfide …
an extracellular α subunit and a membrane spanning β subunit linked together by disulfide …
Dramatic response of a BRAF V600E-mutated primary CNS histiocytic sarcoma to vemurafenib
…, JF Emile, D Galanaud, H Belaid, S de Bernard… - Neurology, 2014 - AAN Enterprises
Histiocytic sarcoma (HS) is classified within the malignant histiocytic disorders. Involvement
of isolated CNS in HS, termed primary CNS-HS (PCNS-HS), is characterized by a …
of isolated CNS in HS, termed primary CNS-HS (PCNS-HS), is characterized by a …
[PDF][PDF] The multi-level regulation of clownfish metamorphosis by thyroid hormones
…, S Miura, M Dussenne, Y Tara, S Lee, S de Bernard… - Cell reports, 2023 - cell.com
Most marine organisms have a biphasic life cycle during which pelagic larvae transform into
radically different juveniles. In vertebrates, the role of thyroid hormones (THs) in triggering …
radically different juveniles. In vertebrates, the role of thyroid hormones (THs) in triggering …
Unique molecular signatures typify skin inflammation induced by chemical allergens and irritants
…, A Mosnier, A Cortial, M Prieux, S De Bernard… - Allergy, 2021 - Wiley Online Library
Background Skin exposure to chemicals may induce an inflammatory disease known as
contact dermatitis (CD). Distinguishing the allergic and irritant forms of CD often proves …
contact dermatitis (CD). Distinguishing the allergic and irritant forms of CD often proves …