User profiles for Sean Ling

Xinsheng Sean Ling (凌新生)

Brown University
Verified email at brown.edu
Cited by 7177

Particulate matter air pollution exposure: role in the development and exacerbation of chronic obstructive pulmonary disease

SH Ling, SF van Eeden - International journal of chronic …, 2009 - Taylor & Francis
Due to the rapid urbanization of the world population, a better understanding of the detrimental
effects of exposure to urban air pollution on chronic lung disease is necessary. Strong …

The association between small airway obstruction and emphysema phenotypes in COPD

WD Kim, SH Ling, HO Coxson, JC English, J Yee… - Chest, 2007 - Elsevier
Background Airflow limitation in COPD is due to a variable combination of small airway
obstruction and centrilobular emphysema (CLE) and/or panlobular emphysema (PLE), but the …

[HTML][HTML] Detection of SARS-CoV-2 antibodies formed in response to the BNT162b2 and mRNA-1237 mRNA vaccine by commercial antibody tests

JN Kanji, A Bailey, J Fenton, SH Ling, R Rivera, S Plitt… - Vaccine, 2021 - Elsevier
Background With rapid approval of SARS-CoV-2 vaccines, the ability of clinical laboratories
to detect vaccine-induced antibodies with available high-throughput commercial assays is …

Patterns of retention of particulate matter in lung tissues of patients with COPD: potential role in disease progression

SH Ling, JE McDonough, JV Gosselink, WM Elliott… - Chest, 2011 - Elsevier
Background Particulate matter (PM) is present in lung tissues of smokers and urban dwellers.
This study was designed to quantify the burden of PM in different lung tissues of subjects …

Effects of a switch from tenofovir‐to abacavir‐based antiretroviral therapy, with or without atazanavir, on renal function

SA Guillemi, SH Ling, JS Dahlby, B Yip… - African Journal of …, 2016 - journals.lww.com
Introduction: Tenofovir disoproxil fumarate (TDF) Áassociated renal dysfunction may abate
when TDF is replaced with abacavir (ABC). The extent to which the third drug atazanavir …

[HTML][HTML] Mechanisms and impact of biofilms and targeting of biofilms using bioactive compounds—A review

…, L Si Jie, C Hooi Sze, A Arif, T Chuan Sean… - Medicina, 2021 - mdpi.com
Biofilms comprising aggregates of microorganisms or multicellular communities have been
a major issue as they cause resistance against antimicrobial agents and biofouling. To date, …

[HTML][HTML] Near-space flight of a correlated photon system

…, YY Sean, C Cheng, C Wildfeuer, A Ling - Scientific reports, 2014 - nature.com
We report the successful test flight of a device for generating and monitoring correlated
photon pairs under near-space conditions up to 35.5 km altitude. Data from ground based …

[HTML][HTML] GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

, … , Swansea, UK Farley Sean 77 Brinkworth Elaine 77 … - Nature, 2023 - nature.com
Critical illness in COVID-19 is an extreme and clinically homogeneous disease phenotype
that we have previously shown 1 to be highly efficient for discovery of genetic associations 2 . …

Sleep-deprived doctors and patient safety: an unresolved link

S Ling - 2023 - repository.rcsi.com
In autumn 2013, Ireland’s non-consultant hospital doctors went on a 24-hour strike to protest
at the Health Service Executive’s lack of compliance with the European Working Time …

The potential and challenges of nanopore sequencing

…, SB Jovanovich, PS Krstic, S Lindsay, XS Ling… - Nature …, 2008 - nature.com
A nanopore-based device provides single-molecule detection and analytical capabilities that
are achieved by electrophoretically driving molecules in solution through a nano-scale pore…