Objective Pulmonary arterial hypertension (PAH) affects up to 15% of patients with connective
tissue diseases (CTDs). Previous recommendations developed as part of larger efforts in …

Diabetic wounds result in significant morbidity, prolonged hospitalization, and enormous
health‐care expenses. Pigs have been shown to have wound healing resembling that in …

Importance Pulmonary hypertension (PH) is a fatal disease. Although the prognosis of
pulmonary arterial hypertension (PAH) has improved with targeted therapies, the outcome is …

Leukocyte and platelet accumulation at sites of cerebral ischemia exacerbate cerebral
damage. The ectoenzyme CD39 on the plasmalemma of endothelial cells metabolizes ADP to …

Deep vein thrombosis (DVT), caused by alterations in venous homeostasis, is the third most
common cause of cardiovascular mortality, however, key molecular determinants in venous …

Objective Systemic sclerosis ( SS c) is associated with interstitial lung disease ( ILD ) and
pulmonary hypertension ( PH ). This study was undertaken to determine the prevalence, …

The surface properties of nanoparticles (NPs) are a major factor that influences how these
nanomaterials interact with biological systems. Interactions between NPs and macrophages of …

The development of microsurgical techniques has facilitated the establishment of fully
vascularized cardiac transplantation models in small mammals. A particularly useful model that …

Ectoenzymes expressed on the surface of vascular cells and leukocytes modulate the
ambient nucleotide milieu. CD73 is an ecto-5′ nucleotidase that catalyzes the terminal …

Introduction Pulmonary arterial hypertension (PAH) is one of the leading causes of mortality
in systemic sclerosis (SSc). We explored the impact of the updated haemodynamic definition …