Roles of oxidants and redox signaling in the pathogenesis of acute respiratory distress syndrome

S Tasaka, F Amaya, S Hashimoto… - Antioxidants & redox …, 2008 - liebertpub.com
The acute respiratory distress syndrome (ARDS) is a disease process that is characterized
by diffuse inflammation in the lung parenchyma and resultant permeability edema. The …

[HTML][HTML] ARDS clinical practice guideline 2021

S Tasaka, S Ohshimo, M Takeuchi, H Yasuda… - Journal of intensive …, 2022 - Springer
Background The joint committee of the Japanese Society of Intensive Care Medicine/Japanese
Respiratory Society/Japanese Society of Respiratory Care Medicine on ARDS Clinical …

Pneumocystis jirovecii pneumonia in non-HIV-infected patients in the era of novel immunosuppressive therapies

S Tasaka, H Tokuda - Journal of Infection and Chemotherapy, 2012 - Springer
In human immunodeficiency virus (HIV)-infected patients, Pneumocystis jirovecii pneumonia
(PCP) is a well-known opportunistic infection, and its management has been established. …

Serum indicators for the diagnosis of pneumocystis pneumonia

S Tasaka, N Hasegawa, S Kobayashi, W Yamada… - Chest, 2007 - Elsevier
Background The diagnosis of pneumocystis pneumonia (PCP) is difficult because it requires
microscopic examination to identify pneumocystis from induced sputum or BAL fluid. Study …

Role of interleukin-6 in bleomycin-induced lung inflammatory changes in mice

F Saito, S Tasaka, K Inoue, K Miyamoto… - American journal of …, 2008 - atsjournals.org
Interleukin-6 (IL-6) is known to be involved in the pathogenesis of various inflammatory
diseases, but its role in bleomycin (BLM)-induced lung injury and subsequent fibrotic changes …

Elevation of KL-6, a lung epithelial cell marker, in plasma and epithelial lining fluid in acute respiratory distress syndrome

…, KH Albertine, H Koh, S Tasaka… - … of Physiology-Lung …, 2004 - journals.physiology.org
KL-6 is a pulmonary epithelial mucin more prominently expressed on the surface membrane
of alveolar type II cells when these cells are proliferating, stimulated, and/or injured. We …

Contribution of high-mobility group box-1 to the development of ventilator-induced lung injury

EN Ogawa, A Ishizaka, S Tasaka, H Koh… - American journal of …, 2006 - atsjournals.org
Rationale: Proinflammatory cytokines play an important role in ventilator-induced lung injury
(VILI). High-mobility group box-1 (HMGB1) is a macrophage-derived proinflammatory …

Role of soluble receptor for advanced glycation end products on endotoxin-induced lung injury

H Zhang, S Tasaka, Y Shiraishi… - American journal of …, 2008 - atsjournals.org
Rationale: The interaction of receptor for advanced glycation end products (RAGE) and its
ligands often leads to inflammatory processes or tissue injury, although the effect of the …

Attenuation of endotoxin-induced acute lung injury by the Rho-associated kinase inhibitor, Y-27632

S Tasaka, H Koh, W Yamada, M Shimizu… - American journal of …, 2005 - atsjournals.org
A small GTPase, Rho, plays key roles in cell adhesion, motility, and contraction after stimulation.
Among Rho effectors isolated, the family of Rho-associated coiled-coil–forming protein …

Comparison of clinical and radiological features of pneumocystis pneumonia between malignancy cases and acquired immunodeficiency syndrome cases: a …

S Tasaka, H Tokuda, F Sakai, T Fujii, K Tateda… - Internal …, 2010 - jstage.jst.go.jp
Background The clinical features of pneumocystis pneumonia (PCP) differ according to the
predisposing factors responsible for immunosuppression. Although PCP in patients with …