Little is known of the molecular mechanisms that trigger oligodendrocyte death and
demyelination in many acute central nervous system insults. Since oligodendrocytes express …

Background Mycobacterium tuberculosis transmission through solid organ transplantation
has been well described, but transmission through transplanted tissues is rare. We …

Rationale: Delays in the diagnosis of tuberculosis (TB) can result in progression to advanced
disease. Patients with pulmonary TB and advanced disease are more likely to transmit …

We combined routinely reported tuberculosis (TB) patient characteristics with genotyping data
and measures of geospatial concentration to predict which small clusters (ie, consisting of …

Background Early identification of outbreaks remains a key component in continuing to
reduce the burden of infectious disease in the United States. Previous studies have applied …

The early identification of clusters of persons with tuberculosis (TB) that will grow to become
outbreaks creates an opportunity for intervention in preventing future TB cases. We used …

A nationwide tuberculosis outbreak linked to a viable bone allograft product contaminated
with Mycobacterium tuberculosis was identified in June 2021. Our subsequent investigation …

The comparative analysis of National Tuberculosis Control Programmes (NTPs) in industrialised,
low-tuberculosis-incidence countries is limited. Analysis of applied methods, function …

Objective This study describes characteristics of large tuberculosis (TB) outbreaks in the
United States detected using novel molecular surveillance methods during 2014–2016 and …

We previously reported use of genotype surveillance data to predict outbreaks among incident
tuberculosis clusters. We propose a method to detect possible outbreaks among endemic …