User profiles for S. Vignot
 | Sébastien VigneauScientist, Dana-Farber Cancer Institute, Boston Verified email at mail.dfci.harvard.edu Cited by 3460 |
[HTML][HTML] mTOR-targeted therapy of cancer with rapamycin derivatives
S Vignot, S Faivre, D Aguirre, E Raymond - Annals of oncology, 2005 - Elsevier
Rapamycin and its derivatives (CCI-779, RAD001 and AP23576) are immunosuppressor
macrolides that block mTOR (mammalian target of rapamycin) functions and yield …
macrolides that block mTOR (mammalian target of rapamycin) functions and yield …
A rationale for chemoradiation (vs radiotherapy) in salivary gland cancers? On behalf of the REFCOR (French rare head and neck cancer network)
T Cerda, XS Sun, S Vignot, PY Marcy, B Baujat… - Critical reviews in …, 2014 - Elsevier
… level through the killing of S phase cells which are relatively … and induces a block at the
G1-S phase of the cell cycle when … concurrent redistribution into S phase and deoxyadenosine …
G1-S phase of the cell cycle when … concurrent redistribution into S phase and deoxyadenosine …
Discrepancies between primary tumor and metastasis: a literature review on clinically established biomarkers
S Vignot, B Besse, F André, JP Spano… - Critical reviews in oncology …, 2012 - Elsevier
The identification of predictive factors of response is critical for the development and
appropriate use of anti-cancer agents. The evaluation of biomarkers is usually performed by …
appropriate use of anti-cancer agents. The evaluation of biomarkers is usually performed by …
[HTML][HTML] A computational approach to distinguish somatic vs. germline origin of genomic alterations from deep sequencing of cancer specimens without a matched …
…, M Montesion, GM Frampton, S Vignot… - PLoS computational …, 2018 - journals.plos.org
… the log-ratio data in segment S i , reflecting the noise … S i , M i the copy number of minor
alleles in S i , distributed as integer 0 ≤ M i ≤ C i/2 , and σ fi the SD of the SNP data at segment S …
alleles in S i , distributed as integer 0 ≤ M i ≤ C i/2 , and σ fi the SD of the SNP data at segment S …
[PDF][PDF] Next-generation sequencing reveals high concordance of recurrent somatic alterations between primary tumor and metastases from patients with non-small-cell …
Purpose Characterization of the genomic changes that drive an individual patient’s disease
is critical in management of many cancers. In patients with non–small-cell lung cancer (…
is critical in management of many cancers. In patients with non–small-cell lung cancer (…
Regulation of extracellular matrix metalloproteinase inducer and matrix metalloproteinase expression by amphiregulin in transformed human breast epithelial cells
S Menashi, M Serova, L Ma, S Vignot, S Mourah… - Cancer research, 2003 - AACR
… using TOPO II TA cloning kit (Invitrogen) following the manufacturer’s recommendations. …
ANOVA and Student’s t test were used to compare differences between groups in various …
ANOVA and Student’s t test were used to compare differences between groups in various …
E-santé et m-santé: état des lieux en 2014 et apports potentiels en oncologie
B Brouard, P Bardo, M Vignot, C Bonnet, S Vignot - Bulletin du cancer, 2014 - Elsevier
… La prise en charge des pathologies cancéreuses est un domaine auquel les possibilités
offertes par la e-santé s’appliquent tout particulièrement. Les prises en charge ambulatoires …
offertes par la e-santé s’appliquent tout particulièrement. Les prises en charge ambulatoires …
[HTML][HTML] Discordance between immunochemistry of mismatch repair proteins and molecular testing of microsatellite instability in colorectal cancer
…, V Randrian, A Duval, M Svrcek, O Lascols, S Vignot… - ESMO open, 2021 - Elsevier
Background DNA mismatch repair system deficiency (dMMR) is found in 15% of colorectal
cancers (CRCs). Two methods are used to determine dMMR, immunohistochemistry (IHC) of …
cancers (CRCs). Two methods are used to determine dMMR, immunohistochemistry (IHC) of …
[HTML][HTML] Comparative analysis of primary tumour and matched metastases in colorectal cancer patients: evaluation of concordance between genomic and …
S Vignot, C Lefebvre, GM Frampton, G Meurice… - European Journal of …, 2015 - Elsevier
Purpose Focal and temporal tumour heterogeneity can represent a major challenge for
biology-guided therapies. This study proposes to investigative molecular discrepancies between …
biology-guided therapies. This study proposes to investigative molecular discrepancies between …
Les traitements des cancers du nasopharynx: revue de la littérature
G Noël, B Dessard-Diana, S Vignot, JJ Mazeron - Cancer/Radiothérapie, 2002 - Elsevier
La radiothérapie classique et les traitements associés ont amélioré le pronostic des cancers
du cavum. Une meilleure sélection des patients qui doivent avoir un traitement plus agressif …
du cavum. Une meilleure sélection des patients qui doivent avoir un traitement plus agressif …