[HTML][HTML] Fast and label-free automated detection of microsatellite status in early colon cancer using artificial intelligence integrated infrared imaging

K Gerwert, S Schörner, F Großerueschkamp… - European Journal of …, 2023 - Elsevier
Purpose Microsatellite instability (MSI) due to mismatch repair (MMR) defects accounts for
15–20% of colon cancers (CC). MSI testing is currently standard of care in CC with …

Mitochondrial cytochrome redox states and respiration in acute pulmonary oxygen sensing

N Sommer, O Pak, S Schörner… - European …, 2010 - Eur Respiratory Soc
Hypoxic pulmonary vasoconstriction (HPV) is an essential mechanism to optimise lung gas
exchange. We aimed to decipher the proposed oxygen sensing mechanism of mitochondria …

[HTML][HTML] A framework for falsifiable explanations of machine learning models with an application in computational pathology

D Schuhmacher, S Schörner, C Küpper… - Medical Image …, 2022 - Elsevier
… Yet, Michalski’s approach of learning structural descriptions from examples lacks an explicit
role of validating hypotheses in a deductive manner. The same problem holds for more …

Growth and doping of semipolar GaN grown on patterned sapphire substrates

…, S Schörner, K Thonke, L Kirste, S Bauer… - Journal of crystal …, 2014 - Elsevier
In order to achieve large area semipolar GaN layers with high crystal quality, we have etched
trenches into n-plane and r-plane sapphire wafers exposing c-plane-like side-walls, from …

[PDF][PDF] Ultrafast in-line capable regeneration process for preventing light induced degradation of boron-doped p-type Cz-silicon PERC solar cells

…, S Schörner, S Gutscher, S Roder, S Rein… - 33rd EU …, 2017 - publica.fraunhofer.de
Solar cells based on boron-doped p-type Czochralski-grown silicon (Cz-Si) substrates suffer
from light-induced degradation (LID) which is related to a metastable boron-oxygen defect …

Dimensionality reduction for deep learning in infrared microscopy: a comparative computational survey

D Müller, D Schuhmacher, S Schörner… - Analyst, 2023 - pubs.rsc.org
While infrared microscopy provides molecular information at spatial resolution in a label-free
manner, exploiting both spatial and molecular information for classifying the disease status …

Doping behavior of GaN grown on patterned sapphire substrates

T Meisch, R Zeller, S Schörner, K Thonke… - … status solidi (b), 2016 - Wiley Online Library
Abstractauthoren We present results of the investigation on the doping behavior of planar
semipolar ‐oriented GaN grown on patterned sapphire substrates mainly focusing on the …

[PDF][PDF] Relationship between pelvic morphology and functional parameters in standing position for patient-specific cup planning in THA

MCM Fischer, S Schörner, S Rohde, C Lüring… - CAOS, 2017 - researchgate.net
The sagittal orientation of the pelvis commonly called pelvic tilt has an effect on the orientation
of the cup in total hip arthroplasty (THA). Pelvic tilt is different between individuals and …

385O Automated detection of microsatellite status in early colon cancer (CC) using artificial intelligence (AI) integrated infrared (IR) imaging on unstained samples …

F Großerüschkamp, SM Schörner, AL Kraeft… - Annals of …, 2021 - annalsofoncology.org
Background Label-free Quantum Cascade Laser (QCL) based IR imaging combined with AI
provides spatially and molecularly resolved alterations in unstained cancer tissue thin …

PD-11 In depth analysis of label-free infrared (IR) imaging-based microsatellite instability (MSI) classification in early colon cancer (CC) on samples from the AIO …

K Gerwert, S Schörner… - Annals of …, 2022 - annalsofoncology.org
Background MSI occurs in 15-20% of all early CC due to a deficient mismatch repair system
and testing is now considered standard for all colon cancers as MSI is of prognostic and …