Epidemiology and clinical management of XDR-TB: a systematic review by TBNET

…, R Centis, S Ruesch-Gerdes… - European …, 2009 - Eur Respiratory Soc
Extensively drug-resistant tuberculosis (XDR-TB) is present in all regions and poses serious
challenges for public health and clinical management. Laboratory diagnosis is difficult and …

[HTML][HTML] Rapid molecular detection of tuberculosis and rifampin resistance

…, DH Persing, S Ruesch-Gerdes… - … England Journal of …, 2010 - Mass Medical Soc
Background Global control of tuberculosis is hampered by slow, insensitive diagnostic
methods, particularly for the detection of drug-resistant forms and in patients with human …

[HTML][HTML] Population-based resistance of Mycobacterium tuberculosis isolates to pyrazinamide and fluoroquinolones: results from a multicountry surveillance project

…, E Qadeer, L Rigouts, S Ruesch-Gerdes… - The Lancet infectious …, 2016 - thelancet.com
Background Pyrazinamide and fluoroquinolones are essential antituberculosis drugs in new
rifampicin-sparing regimens. However, little information about the extent of resistance to …

[HTML][HTML] Multidrug-and extensively drug-resistant tuberculosis, Germany

…, D Kirsten, T Schaberg, S Ruesch-Gerdes… - Emerging infectious …, 2008 - ncbi.nlm.nih.gov
We evaluated risk factors and treatment outcomes associated with multidrug-resistant (MDR)
and extensively drug-resistant (XDR) tuberculosis (TB) in Germany in 2004–2006. In 177 (4…

A multisite assessment of the quantitative capabilities of the Xpert MTB/RIF assay

…, D Hillemann, S Ruesch-Gerdes… - American journal of …, 2011 - atsjournals.org
Rationale: The Xpert MTB/RIF is an automated molecular test for Mycobacterium tuberculosis
that estimates bacterial burden by measuring the threshold-cycle (Ct) of its M. tuberculosis–…

[HTML][HTML] Recommendations of the German Central Committee against Tuberculosis (DZK) and the German Respiratory Society (DGP) for the diagnosis and treatment …

…, A Reuss, K Schenkel, S Ruesch-Gerdes… - …, 2016 - thieme-connect.com
Non-tuberculous mycobacterioses comprise a group of diseases caused by mycobacteria
which do not belong to the Mycobacterium (M.) tuberculosis-complex and are not ascribed to M…

Epidemiology of antituberculosis drug resistance 2002–07: an updated analysis of the Global Project on Anti-Tuberculosis Drug Resistance Surveillance

…, D Falzon, SR Gerdes, K Feldman, S Hoffner… - The Lancet, 2009 - thelancet.com
Background The Global Project on Anti-Tuberculosis Drug Resistance has been gathering
data since 1994. This study provides the latest data on the extent of drug resistance worldwide…

[HTML][HTML] Multidrug-resistant tuberculosis in central Asia

…, JD Orozco, R Male, S Ruesch-Gerdes… - Emerging infectious …, 2004 - ncbi.nlm.nih.gov
Multidrug-resistant tuberculosis (MDR-TB) has emerged as a major threat to TB control,
particularly in the former Soviet Union. To determine levels of drug resistance within a directly …

[HTML][HTML] Mycobacterium tuberculosis drug resistance, Ghana

…, T Kubica, S Niemann, S Ruesch-Gerdes - Emerging infectious …, 2006 - ncbi.nlm.nih.gov
Several infection risk factors exist simultaneously in this situation. In a CL-endemic area,
immigrant populations, who are mostly nonimmune, exert pressure on the environment (…

[HTML][HTML] External quality assessment for tuberculosis diagnosis and drug resistance in the European Union: a five year multicentre implementation study

…, C Kodmon, F Drobniewski, S Ruesch-Gerdes… - PLoS …, 2016 - journals.plos.org
Background External quality assurance (EQA) systems are essential to ensure accurate
diagnosis of TB and drug-resistant TB. The implementation of EQA through organising regular …