User profiles for S. Pattenden
Samantha G PattendenAssociate Professor, University of North Carolina at Chapel Hill Verified email at unc.edu Cited by 3343 |
Parental smoking and children's respiratory health: independent effects of prenatal and postnatal exposure
S Pattenden, T Antova, M Neuberger… - Tobacco …, 2006 - tobaccocontrol.bmj.com
Objectives: Adverse effects have been reported of prenatal and/or postnatal passive exposure
to smoking on children’s health. Uncertainties remain about the relative importance of …
to smoking on children’s health. Uncertainties remain about the relative importance of …
International study of temperature, heat and urban mortality: the 'ISOTHURM'project
…, RS Kovats, S Pattenden, S Hajat… - International journal …, 2008 - academic.oup.com
Background This study describes heat- and cold-related mortality in 12 urban populations in
low- and middle-income countries, thereby extending knowledge of how diverse populations…
low- and middle-income countries, thereby extending knowledge of how diverse populations…
A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells
…, X Huang, CD Simpson, SG Pattenden… - Nature chemical …, 2011 - nature.com
… Protein lysine methyltransferases (PKMTs) catalyze the transfer of a methyl group from S-adenosyl-L-methionine
(SAM) to the ɛ-amino group of lysine residues of proteins, including …
(SAM) to the ɛ-amino group of lysine residues of proteins, including …
An orally bioavailable chemical probe of the lysine methyltransferases EZH2 and EZH1
…, M Rougie, A Jiang, SG Pattenden… - ACS chemical …, 2013 - ACS Publications
… However, it is not clear how the structural changes contribute to the switch from GSK126’s
high EZH2/EZH1 selectivity (>150-fold) to UNC1999’s low EZH2/EZH1 selectivity (…
high EZH2/EZH1 selectivity (>150-fold) to UNC1999’s low EZH2/EZH1 selectivity (…
Vulnerability to winter mortality in elderly people in Britain: population based study
P Wilkinson, S Pattenden, B Armstrong, A Fletcher… - Bmj, 2004 - bmj.com
Objective To examine the determinants of vulnerability to winter mortality in elderly British
people. Design Population based cohort study (119 389 person years of follow up). Setting …
people. Design Population based cohort study (119 389 person years of follow up). Setting …
Preferential occupancy of histone variant H2AZ at inactive promoters influences local histone modifications and chromatin remodeling
The yeast histone variant H2AZ (Htz1) is implicated in transcription activation, prevention of
the ectopic spread of heterochromatin, and genome integrity. Our genome-wide localization …
the ectopic spread of heterochromatin, and genome integrity. Our genome-wide localization …
Mortality and temperature in Sofia and London
S Pattenden, B Nikiforov, BG Armstrong - Journal of Epidemiology & …, 2003 - jech.bmj.com
Study objective: Heat and cold have been associated with increased mortality, independently
of seasonal trends, but details are little known. This study explores associations between …
of seasonal trends, but details are little known. This study explores associations between …
Parental smoking and lung function in children: an international study
…, U Gehring, F Hruba, S Pattenden… - American journal of …, 2006 - atsjournals.org
… symptoms is reported separately (S. Pattenden and colleagues, unpublished data). … (18),
except for minimum exhalation time of 6 s (not feasible for children) and except for the Dutch …
except for minimum exhalation time of 6 s (not feasible for children) and except for the Dutch …
Selective inhibition of EZH2 and EZH1 enzymatic activity by a small molecule suppresses MLL-rearranged leukemia
…, T Parton, KD Konze, SG Pattenden… - Blood, The Journal …, 2015 - ashpublications.org
Enhancer of zeste homolog 2 (EZH2) and related EZH1 control gene expression and promote
tumorigenesis via methylating histone H3 at lysine 27 (H3K27). These methyltransferases …
tumorigenesis via methylating histone H3 at lysine 27 (H3K27). These methyltransferases …
Cold comfort: The social and environmental determinants of excess winter deaths in England, 1986-96
…, M Landon, B Armstrong, S Stevenson, S Pattenden… - 2006 - policycommons.net
The nature of the study means that misclassifcation of the temperature characteristics of
dwellings is inevitable, and this is likely to lead to underestimation of the influence of home …
dwellings is inevitable, and this is likely to lead to underestimation of the influence of home …