User profiles for S. Nagata

Shigekazu Nagata

Immunology Frontier Research Center, Osaka University
Verified email at ifrec.osaka-u.ac.jp
Cited by 117955

[HTML][HTML] Apoptosis by death factor

S Nagata - cell, 1997 - cell.com
There is an old Japanese saying that “Once we are in the land of the living, we will eventually
die.” This is true, not only for human beings, but also for the cells that constitute our bodies. …

[HTML][HTML] Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

…, UM Moll, C Muñoz-Pinedo, S Nagata… - Cell Death & …, 2018 - nature.com
Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated
guidelines for the definition and interpretation of cell death from morphological, biochemical, …

The Solar Optical Telescope for the Hinode Mission: An Overview

S Tsuneta, K Ichimoto, Y Katsukawa, S Nagata… - Solar Physics, 2008 - Springer
… V ; with 0.2-s exposure we can measure Q, U, or V ; and with 0.1-s exposure, we can measure
… Up to 0.4-s exposures are possible for V , and up to 0.2-s exposures for Q and U. Note that …

Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family

T Suda, T Takahashi, P Golstein, S Nagata - Cell, 1993 - cell.com
… were heated at 95OC for 2 min in Laemmli’s sample buffer containing 5% P-… were collected
and expanded in Dulbecco’s modified Eagle’s medium (DMEM) containing 10% FCS and 50 …

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

…, H Yokoyama, K Okawa, A Iwamatsu, S Nagata - Nature, 1998 - nature.com
… a nuclease or its activating molecule(s) is generated in cells … a proform of the molecule(s)
that induces DNA degradation 14 . We … We also tested for the presence of an inhibitor(s) of DNA …

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

…, M Sameshima, A Hase, Y Seto, S Nagata - Cell, 1991 - cell.com
… Monkey COS-7 cells (ATCC CRL1651) and mouse L929 cells were grown in Dulbecco’s
modified Eagle’s medium (DMEM) containing 10% FCS. Production of mouse anti-Fas …

Molecular cloning and expression of cDNA for human granulocyte colony-stimulating factor

S Nagata, M Tsuchiya, S Asano, Y Kaziro, T Yamazaki… - Nature, 1986 - nature.com
Granulocyte colony-stimulating factor (G-CSF) is a member of the CSF family of hormone-like
glycoproteins that regulate haematopoietic cell proliferation and differentiation 1,2 , and G-…

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

…, CI Brannan, NG Copeland, NA Jenkins, S Nagata - Nature, 1992 - nature.com
… The sequencing reaction was done by the dideoxynucleotide chain-termination method
using T7-DNA polymerase (Pharmacia) and [a-"S]dATPa S (Amersham). As primers for the …

The Fas death factor

S Nagata, P Golstein - Science, 1995 - science.org
Fas ligand (FasL), a cell surface molecule belonging to the tumor necrosis factor family, binds
to its receptor Fas, thus inducing apoptosis of Fas-bearing cells. Various cells express Fas, …

Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis

H Sakahira, M Enari, S Nagata - Nature, 1998 - nature.com
… ICAD-L for the long form and ICAD-S for the short form 10 , which seem to be generated by
alternative splicing. Both ICAD-L and ICAD-S carry two putative cleavage sites for caspase 3 (…