Blockade of inflammation and airway hyperresponsiveness in immune-sensitized mice by dominant-negative phosphoinositide 3-kinase–TAT

S Myou, AR Leff, S Myo, E Boetticher, J Tong… - The Journal of …, 2003 - rupress.org
Phosphoinositide 3-kinase (PI3K) is thought to contribute to the pathogenesis of asthma by
effecting the recruitment, activation, and apoptosis of inflammatory cells. We examined the …

Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level

CJ Chen, HI Yang, JUN Su, CL Jen, SL You, SN Lu… - Jama, 2006 - jamanetwork.com
ContextSerum hepatitis B virus (HBV) DNA level is a marker of viral replication and efficacy
of antiviral treatment in individuals with chronic hepatitis B.ObjectiveTo evaluate the …

Acute eosinophilic pneumonia following cigarette smoking: a case report including cigarette-smoking challenge test

…, M Yasui, S Myou, T Kita, A Watanabe, S Nakao - Internal …, 2002 - jstage.jst.go.jp
A21-year-old womanpresented with acute progressive dyspnea. Chest computed tomography
(CT) revealed dif-fuse bilateral infiltrates. Based on the results of transbronchial lung …

Antitussive effects of the leukotriene receptor antagonist montelukast in patients with cough variant asthma and atopic cough

…, S Nomura, Y Ishiura, S Myou, S Nakao - Allergology …, 2010 - Elsevier
… Randomization was performed by each physician based on the patient’s chart number.
Drugs were administrated to patients with CVA or AC during 2 weeks from the second visit (…

[HTML][HTML] Change in bronchial responsiveness and cough reflex sensitivity in patients with cough variant asthma: effect of inhaled corticosteroids

M Fujimura, J Hara, S Myou - Cough, 2005 - Springer
Background Cough variant asthma (CVA) is a cause of chronic cough and a precursor of
typical asthma. We retrospectively examined the longitudinal change in bronchial …

Vitamin K administration to elderly patients with osteoporosis induces no hemostatic activation, even in those with suspected vitamin K deficiency

H Asakura, S Myou, Y Ontachi, T Mizutani… - Osteoporosis …, 2001 - Springer
The administration of menaquinone-4 (MK-4), one of subclasses of vitamin K 2 , significantly
reduces bone loss in postmenopausal osteoporotic women. However, concerns have been …

Characterization of increased cough sensitivity after antigen challenge in guinea pigs

Q Liu, M Fujimura, H Tachibana, S Myou… - Clinical & …, 2001 - Wiley Online Library
Increased sensitivity of cough reflex is a fundamental feature of bronchodilator resistant non‐productive
cough associated with eosinophilic tracheobronchitis. Our hypothesis is that …

[HTML][HTML] Human group V phospholipase A2 induces group IVA phospholipase A2-independent cysteinyl leukotriene synthesis in human eosinophils

…, SK Han, E Boetticher, E O'Leary, S Myou… - Journal of Biological …, 2003 - ASBMB
… Multiple forms of PLA 2 s, including a number of secretory PLA 2 s (sPLA 2 ) ( … Accumulating
evidence has indicated that some sPLA 2 s work in concert with cPLA 2 to induce eicosanoid …

Ambroxol for the prevention of acute upper respiratory disease

…, M Fujimura, Y Ishiura, S Myou, S Nakao - Clinical and Experimental …, 2006 - Springer
Although acute upper respiratory diseases (AURDs) such as common cold and influenza
are common, few interventions have been proven to be effective in their prevention and …

Regulation of Interleukin-5–Induced β2-Integrin Adhesion of Human Eosinophils by Phosphoinositide 3-Kinase

M Sano, AR Leff, S Myou, E Boetticher… - American journal of …, 2005 - atsjournals.org
We examined the role of phosphoinositide 3-kinase (PI3K) in integrin-mediated eosinophil
adhesion. Δp85, a dominant-negative form of the class IA PI3K adaptor subunit, was fused to …