Cough is one of the most common presenting symptoms of COVID-19, along with fever and
loss of taste and smell. Cough can persist for weeks or months after SARS-CoV-2 infection, …

Chronic cough is globally prevalent across all age groups. This disorder is challenging to treat
because many pulmonary and extrapulmonary conditions can present with chronic cough…

Background Unexplained chronic cough (UCC) causes significant impairments in quality of
life. Effective assessment and treatment approaches are needed for UCC. Methods This …

… 1) each item‘s face validity was … s alpha coefficients which indicate the extent to which the
items are interrelated. Internal reliability is generally acceptable for domains with a Cronbach‘s …

… Therefore, only coughs occurring within 15 s of capsaicin and citric acid delivery should be
counted 10, 25, 30, 31. Coughs that occur beyond this time period may not be capsaicin or …

These guidelines incorporate the recent advances in chronic cough pathophysiology, diagnosis
and treatment. The concept of cough hypersensitivity has allowed an umbrella term that …

Background Gefapixant is an oral P2X 3 receptor antagonist that has previously shown efficacy
and safety in refractory chronic cough and unexplained chronic cough. We therefore aim …

… The inspiratory flow was standardised at 0·5 L/s with an inspiratory flow regulator valve.
We counted coughs for 30 s after exposure to each dose, during which the participant's rated …

Background: An association between the sputum eosinophil count and the response to a 2
week course of prednisolone has previously been reported in patients with chronic …

Background We performed systematic reviews using the population, intervention, comparison,
outcome (PICO) format to answer the following key clinical question: Are the CHEST 2006 …