… to transfer forces between the user’s pelvis and torso. The Lowe’s/Virginia Tech device also
uses … In contrast to the use of carbon fiber rods in the Lowe’s/Virginia Tech exoskeleton and …

… 1) allows specific binding to members of the ErbB receptor family (Anastasi et al., 2003;
Zhang et al., 2007). RALT inhibits downstream EGFR signalling, including activation of ERKs …

Present transfusional regimen protocols increase the life expectancy of patients with beta-thalassemia
major, but cause a progressive iron overload that can be prevented or limited only …

As a rule, hepatocyte growth factor/scatter factor (HGF/SF) is produced by mesenchymal cells,
while its receptor, the tyrosine kinase encoded by the met proto-oncogene, is expressed …

… the identification of the molecular mechanism(s) through which RALT exerts its essential role
of EGFR inhibitor and putative tumor suppressor function (Anastasi et al., 2005; Ferby et al., …

… S Anastasi dedicates this work to the loving memory of his mother. We thank Y Yarden and
J Sap for reagents and C Full for tissue culture work. MF is the recipient of an AIRC fellowship…

An emerging paradigm holds that loss of negative signalling to receptor tyrosine kinases (RTKs)
is permissive for their oncogenic activity. Herein, we have addressed tumor suppression …

… ) with a post hoc Bonferroni’s test was used for multiple sample comparisons. Student’s t
test (unpaired, two-… We thank S. Alemà and G. Blandino for critical reading of the manuscript. …

Physiological signalling by the epidermal growth factor receptor (EGFR) controls developmental
processes and tissue homeostasis, whereas aberrant EGFR activity drives oncogenic …

The purpose of the study was to investigate determinants of acute mountain sickness after
rapid ascent to high altitude. A total of 21 climbers were studied ascending from <1,200 m to …