Background Cancer‐related pain is complex and multi‐dimensional but the mainstay of
cancer pain management has predominantly used a biomedical approach. There is a need for …

Purpose Dry mouth (xerostomia) is one of the commonest symptoms in cancer patients and
can adversely affect quality of life. The aim of this review was to determine the effectiveness …

Cancer-related pain is complex and multi-dimensional; yet, the mainstay of cancer pain
management has been the biomedical approach. There is a need for nonpharmacological and …

… context of chronic daily breathlessness, rather than acute exacerbations (we did not use the
“worst breathlessness over the past 24 hours” measure that we also had from the Oxberry et …

Aims To assess the effect of oral opioids vs. placebo on breathlessness in patients with
chronic heart failure (CHF). Methods and results Oral morphine (Oramorph), oral oxycodone (…

Chronic refractory breathlessness is common and distressing in advanced disease. Despite
level I evidence to support the use of opioids for this symptom, not all patients benefit. This …

… To allow for the repeat observations in the Oxberry et al. and Oxygen HF studies, we used
robust standard errors, with each person in those studies being defined as a cluster. This does …

OBJECTIVES: The aim of the study was to determine the minimally clinically important
difference (MCID) for breathlessness due to chronic heart failure (CHF). BACKGROUND: The …

Therapeutic Reviews aim to provide essential independent information for health professionals
about drugs used in palliative and hospice care. Additional content is available on www.…

Aims Chronic breathlessness is a major symptom for patients with compensated chronic
heart failure (CHF) and its impact is different to the breathlessness resulting from pulmonary …