User profiles for S. B. Carr

Stephen B Carr

Research Complex at Harwell
Verified email at rc-harwell.ac.uk
Cited by 1520

[HTML][HTML] Future therapies for cystic fibrosis

L Allen, L Allen, SB Carr, G Davies, D Downey… - Nature …, 2023 - nature.com
We are currently witnessing transformative change for people with cystic fibrosis with the
introduction of small molecule, mutation-specific drugs capable of restoring function of the …

Clinical immunology review series: An approach to the management of pulmonary disease in primary antibody deficiency

MD Tarzi, S Grigoriadou, SB Carr… - Clinical & …, 2009 - Wiley Online Library
The sinopulmonary tract is the major site of infection in patients with primary antibody
deficiency syndromes, and structural lung damage arising from repeated sepsis is a major …

An update on CFTR modulators as new therapies for cystic fibrosis

JA King, AL Nichols, S Bentley, SB Carr, JC Davies - Pediatric Drugs, 2022 - Springer
Over the past decade there have been significant developments in the field of Cystic Fibrosis
Transmembrane Regulator modulator drugs. Following treatment in patients with cystic …

Lung clearance index at 4 years predicts subsequent lung function in children with cystic fibrosis

…, S Lum, A Bush, J Price, SB Carr… - American journal of …, 2011 - atsjournals.org
Rationale: The markedly improved life expectancy of children with cystic fibrosis (CF) has
created a new challenge, as traditional markers of lung disease are frequently normal in young …

Early detection of cystic fibrosis lung disease: multiple-breath washout versus raised volume tests

…, H Ljungberg, G Hülskamp, A Bush, SB Carr… - Thorax, 2007 - thorax.bmj.com
Background: Lung clearance index (LCI), a measure of ventilation inhomogeneity derived
from the multiple-breath inert gas washout (MBW) technique, has been shown to detect …

Randomised controlled trial of nasal continuous positive airways pressure (CPAP) in bronchiolitis

…, CC Minasian, WJ Kozlowska, SB Carr - Archives of Disease in …, 2008 - adc.bmj.com
Aims: To compare continuous positive airways pressure (CPAP) with standard treatment (ST)
in the management of bronchiolitis. Methods: Children <1 year of age with bronchiolitis and …

Lung Clearance Index and HRCT are complementary markers of lung abnormalities in young children with CF

…, A Bush, A Wade, C Oliver, A Calder, J Price, SB Carr… - Thorax, 2011 - thorax.bmj.com
Rationale High resolution computed tomography (HRCT) is a more sensitive tool for detecting
early cystic fibrosis (CF) lung disease than either spirometry or plain radiography, but its …

[HTML][HTML] A multinational report to characterise SARS-CoV-2 infection in people with cystic fibrosis

…, R Ruseckaite, AL Stephenson, SB Carr… - Journal of cystic …, 2020 - Elsevier
Abstract Information is lacking on the clinical impact of the novel coronavirus, SARS-CoV-2,
on people with cystic fibrosis (CF). Our aim was to characterise SARS-CoV-2 infection in …

Lung function is abnormal in 3-month-old infants with cystic fibrosis diagnosed by newborn screening

…, S Lum, D Ahmed, I Balfour-Lynn, SB Carr… - Thorax, 2012 - thorax.bmj.com
Background Long-term benefits of newborn screening (NBS) for cystic fibrosis (CF) have
been established with respect to nutritional status, but effects on pulmonary health remain …

[HTML][HTML] The global impact of SARS-CoV-2 in 181 people with cystic fibrosis

…, LVR da Silva Filho, J Melo, M Zampoli, SB Carr… - Journal of cystic …, 2020 - Elsevier
With the growing SARS-CoV-2 pandemic, we need to better understand its impact in specific
patient groups like those with Cystic Fibrosis (CF). We report on 181 people with CF (32 …