Theophylline, a known phosphodiesterase inhibitor, has been widely used as an additional
bronchodilator in asthmatic patients who are not adequately controlled on high-doses of …

PURPOSE: It has been reported that among other factors, smoking may enhance respiratory
muscle strength in healthy subjects (Chen H. et al Appl Physiol 1989; 66: 943-8). In this …

… is 41.9 and mean BMI measured is 31.47. The mean for the pretest probability score
STOP-BANG recorded is … A limitation of this study is the small sample size. Therefore, studies with …

… COPD is characterized by airflow limitation that is not fully reversible and spirometry is
essential for the definite diagnosis of this disorder. There is accumulating evidence that early …

… , and potentially antiviral mechanisms, is an interesting proposal as an adjuvant in the
treatment of COVID-19 patients. Nevertheless, it is essential to understand how this compound …

… Chronic obstructive pulmonary disease (COPD) is characterised by airflow limitation that is
not fully reversible. The development of COPD depends on the patient’s exposure to noxious …

… However, the degree of inhibition is small at concentrations of theophylline that are … lung
extracts is inhibited by only 5–10% by therapeutic concentrations of theophylline [6]. There is …

… IL-5 is demonstrated to be increased in the bronchial tissue of BA patients [17]. IL-13 is
another Th2 cytokine [18] that is shown not only to enhance IgE synthesis [19], but also to directly …

… syndrome is the most common sleep disordered breathing (SDB) and is associated with
recurrent episodes of upper airway (UA) collapse during sleep. Arousal from sleep is required to …

… is highly prevalent in patients with severe COPD and is associated with substantial impairments
in psychological and physical functioning. There is strong evidence that depression is …