User profiles for Ryan Arathimos
 | Ryan ArathimosKing's College London Verified email at kcl.ac.uk Cited by 772 |
[HTML][HTML] Epigenome-wide association study of asthma and wheeze in childhood and adolescence
Background Asthma heritability has only been partially explained by genetic variants and is
known to be sensitive to environmental factors, implicating epigenetic modifications such as …
known to be sensitive to environmental factors, implicating epigenetic modifications such as …
Genetic and observational evidence supports a causal role of sex hormones on the development of asthma
Introduction Males have a higher prevalence of asthma in childhood, whereas females have
a higher prevalence in adolescence and adulthood. The ‘adolescent switch’ observed …
a higher prevalence in adolescence and adulthood. The ‘adolescent switch’ observed …
[HTML][HTML] Vitamin D and the risk of treatment-resistant and atypical depression: a Mendelian randomization study
Observational evidence has implicated vitamin D levels as a risk factor in major depressive
disorder (MDD). Confounding or reverse causation may be driving these observed …
disorder (MDD). Confounding or reverse causation may be driving these observed …
Genetic risk for Alzheimer's disease, cognition, and mild behavioral impairment in healthy older adults
Background The neuropsychiatric syndrome mild behavioral impairment (MBI) describes an
at‐risk state for dementia and may be a useful screening tool for sample enrichment. We …
at‐risk state for dementia and may be a useful screening tool for sample enrichment. We …
[HTML][HTML] Epigenome-wide association study of lung function level and its change
…, G Erhart, F Kronenberg, R Arathimos… - European …, 2019 - Eur Respiratory Soc
Previous reports link differential DNA methylation (DNAme) to environmental exposures that
are associated with lung function. Direct evidence on lung function DNAme is, however, …
are associated with lung function. Direct evidence on lung function DNAme is, however, …
[HTML][HTML] Epigenome-wide meta-analysis of DNA methylation and childhood asthma
Background Epigenetic mechanisms, including methylation, can contribute to childhood
asthma. Identifying DNA methylation profiles in asthmatic patients can inform disease …
asthma. Identifying DNA methylation profiles in asthmatic patients can inform disease …
Maternal alcohol consumption and offspring DNA methylation: findings from six general population-based birth cohorts
GC Sharp, R Arathimos, SE Reese, CM Page… - …, 2018 - Future Medicine
Aim: Alcohol consumption during pregnancy is sometimes associated with adverse outcomes
in offspring, potentially mediated by epigenetic modifications. We aimed to investigate …
in offspring, potentially mediated by epigenetic modifications. We aimed to investigate …
Dmrff: Identifying differentially methylated regions efficiently with power and control
A differentially methylated region (DMR) is a genomic region in which DNA methylation is
consistently positively or negatively associated with a phenotype or exposure. We demonstrate …
consistently positively or negatively associated with a phenotype or exposure. We demonstrate …
Multiple measures of depression to enhance validity of major depressive disorder in the UK Biobank
BackgroundThe UK Biobank contains data with varying degrees of reliability and
completeness for assessing depression. A third of participants completed a Mental Health …
completeness for assessing depression. A third of participants completed a Mental Health …
Late‐life onset psychotic symptoms and incident cognitive impairment in people without dementia: Modification by genetic risk for Alzheimer's disease
Introduction Late‐life onset psychosis is associated with faster progression to dementia in
cognitively normal people, but little is known about its relationship with cognitive impairment in …
cognitively normal people, but little is known about its relationship with cognitive impairment in …