[HTML][HTML] Respiratory and cardiovascular responses to walking down a traffic-polluted road compared with walking in a traffic-free area in participants aged 60 years …

R Sinharay, J Gong, B Barratt, P Ohman-Strickland… - The Lancet, 2018 - thelancet.com
Background Long-term exposure to pollution can lead to an increase in the rate of decline
of lung function, especially in older individuals and in those with chronic obstructive …

[HTML][HTML] Relationship between free and total malondialdehyde, a well-established marker of oxidative stress, in various types of human biospecimens

…, H Han, L He, Y Teng, T Tetley, R Sinharay… - Journal of thoracic …, 2018 - ncbi.nlm.nih.gov
Background Oxidative stress is involved in thoracic diseases and health responses to air
pollution. Malondialdehyde (MDA) is a well-established marker of oxidative stress, but it may be …

The human circulating miRNome reflects multiple organ disease risks in association with short-term exposure to traffic-related air pollution

…, M Chadeau-Hyam, R Sinharay… - Environment …, 2018 - Elsevier
Traffic-related air pollution is a complex mixture of particulate matter (PM) and gaseous
pollutants, such as nitrogen dioxide (NO2). PM exposure contributes to the pathogenesis of many …

[HTML][HTML] Impact of short-term traffic-related air pollution on the metabolome–Results from two metabolome-wide experimental studies

…, P Cullinan, KF Chung, P Collins, R Sinharay… - Environment …, 2019 - Elsevier
Exposure to traffic-related air pollution (TRAP) has been associated with adverse health
outcomes but underlying biological mechanisms remain poorly understood. Two randomized …

Cys34 adductomes differ between patients with chronic lung or heart disease and healthy controls in central London

…, WMB Edmands, S Dagnino, R Sinharay… - … science & technology, 2018 - ACS Publications
Oxidative stress generates reactive species that modify proteins, deplete antioxidant defenses,
and contribute to chronic obstructive pulmonary disease (COPD) and ischemic heart …

Sputum-to-serum hydrogen sulfide ratio in COPD

…, C Rossios, D Gibeon, P Macedo, R Sinharay… - Thorax, 2014 - thorax.bmj.com
Objectives Hydrogen sulfide (H 2 S) is a gas produced by respiratory cells including smooth
muscle cells and may play a role as a cellular gasotransmitter. We evaluated whether H 2 S …

Relationships between airborne pollutants, serum albumin adducts and short-term health outcomes in an experimental crossover study

…, SM Rappaport, KF Chung, P Cullinan, R Sinharay… - Chemosphere, 2020 - Elsevier
Exposure to air pollution can have both short-term and long-term effects on health. However,
the relationships between specific pollutants and their effects can be obscured by …

Hydrogen sulfide (H2S) in sputum and serum as a novel biomarker of COPD

…, D Gibeon, P Macedo, R Sinharay… - European …, 2014 - Eur Respiratory Soc
Objectives: Hydrogen sulphide (H 2 S) is a gas produced by respiratory cells including smooth
muscle cells and may play a role as a cellular gasotransmitter. The aim of the study is to …

[BOOK][B] Oxford Assess and Progress: Clinical Medicine

D Furmedge, R Sinharay - 2019 - books.google.com
Maximise your exam success with this essential revision guide. The third edition of Oxford
Assess and Progress: Clinical Medicine features over 550 Single Best Answer questions. …

Preventing future chest drain related deaths

T Khan, C Ross, R Sinharay, M Park, A O'Mahony… - 2023 - Eur Respiratory Soc
Background: Chest drain malposition is a well recognized safety issue. In 2008, the UK
National Patient Safety Agency issued a safety alert regarding chest drain insertion after …