Immunogenicity and crossreactivity of antibodies to the nucleocapsid protein of SARS-CoV-2: utility and limitations in seroprevalence and immunity studies

…, J Chi, NR Melero, M Popovic, R López-Aladid… - Translational …, 2021 - Elsevier
COVID-19 patients elicit strong responses to the nucleocapsid (N) protein of SARS-CoV-2
but binding antibodies are also detected in prepandemic individuals, indicating potential …

SARS-CoV-2–induced acute respiratory distress syndrome: pulmonary mechanics and gas-exchange abnormalities

…, A Soriano, R Mellado, R López-Aladid… - Annals of the …, 2020 - atsjournals.org
Methods Descriptive analysis included 50 consecutive patients with laboratory-confirmed
SARS-CoV-2 infection who developed ARDS (9) and underwent IMV. These patients were …

Resistance mechanisms and molecular epidemiology of Pseudomonas aeruginosa strains from patients with bronchiectasis

…, R Amaro, R López-Aladid… - Journal of …, 2022 - academic.oup.com
Background Non-cystic fibrosis bronchiectasis (BE) is a chronic structural lung condition
that facilitates chronic colonization by different microorganisms and courses with recurrent …

[HTML][HTML] Determining the most accurate 16S rRNA hypervariable region for taxonomic identification from respiratory samples

R López-Aladid, L Fernández-Barat… - Scientific reports, 2023 - nature.com
16S rRNA gene profiling, which contains nine hypervariable regions (V1–V9), is the gold
standard for identifying taxonomic units by high-throughput sequencing. Microbiome studies …

[HTML][HTML] Improvement in detecting cytomegalovirus drug resistance mutations in solid organ transplant recipients with suspected resistance using next generation …

R López-Aladid, A Guiu, MM Mosquera… - PLoS …, 2019 - journals.plos.org
Objetives The aim of this study was to identify CMV drug resistance mutations (DRM) in
solid organ transplant (SOT) recipients with suspected resistance comparing next-generation …

Label-free plasmonic biosensor for rapid, quantitative, and highly sensitive COVID-19 serology: Implementation and clinical validation

…, L Bueno, R López-Aladid… - Analytical …, 2021 - ACS Publications
Serological tests are essential for the control and management of COVID-19 pandemic (diagnostics
and surveillance, and epidemiological and immunity studies). We introduce a direct …

[HTML][HTML] Molecular characterization of methicillin-resistant Staphylococcus aureus clinical strains from the endotracheal tubes of patients with nosocomial pneumonia

…, L Fernández-Barat, A Motos, R López-Aladid… - … Resistance & Infection …, 2020 - Springer
Background Among all cases of nosocomial pneumonia, Staphylococcus aureus is the
second most prevalent pathogen (17.8%). In Europe, 29.9% of the isolates are oxacillin-resistant. …

[HTML][HTML] Reconsidering ventilator-associated pneumonia from a new dimension of the lung microbiome

L Fernández-Barat, R López-Aladid, A Torres - EBioMedicine, 2020 - thelancet.com
Complex microbial communities that reside in the lungs, skin and gut are now appreciated
for their role in maintaining organ, tissue and immune homoeostasis. As lungs are currently …

The value of serology testing to manage SARS-CoV-2 infections

L Fernández-Barat, R López-Aladid… - European Respiratory …, 2020 - Eur Respiratory Soc
The figures presented in the World Health Organization's latest report on the current status
of the coronavirus disease 2019 (COVID-19) pandemic and the COVID-19 dashboard of the …

Detection of cytomegalovirus drug resistance mutations in solid organ transplant recipients with suspected resistance

R López-Aladid, A Guiu, G Sanclemente… - Journal of Clinical …, 2017 - Elsevier
Background Current guidelines recommend that treatment of resistant cytomegalovirus (CMV)
in solid organ transplant (SOT) recipients must be based on genotypic analysis. However, …