Objective. —To assess the efficacy of adjunctive monoclonal antibody antiendotoxin
immunotherapy in patients with gram-negative sepsis. Design. —Double-blind, randomized, …

Recently, “Technical standards for respiratory oscillometry” was published, which reviewed
the physiological basis of oscillometric measures and detailed the technical factors related to …

Inhaled therapies are the backbone of asthma and chronic obstructive pulmonary disease
management, helping to target therapy at the airways. Adherence to prescribed treatment is …

175 years have elapsed since John Hutchinson introduced the world to his version of an
apparatus that had been in development for nearly two centuries, the spirometer. Though he …

Rationale: Adults may exhibit characteristics of both asthma and chronic obstructive pulmonary
disease (COPD), a situation recently described as asthma–COPD overlap (ACO). There …

Noninvasiveness, low cooperation demand and the potential for detailed physiological
characterisation have promoted the use of oscillometry in the assessment of lung function. …

Oscillometry is gaining in clinical use and while there is an increased interest in the technique,
there is paucity in the understanding of its possibilities and limitations. Oscillometry has …

Background The particle size of inhaled corticosteroids (ICSs) may affect airway drug
deposition and effectiveness. Objective To compare the effectiveness of extrafine ICSs (mass …

Developed over six decades ago, pulmonary oscillometry has re‐emerged as a noninvasive
and effort‐independent method for evaluating respiratory‐system impedance in patients …

Purpose To determine if proton ( 1 H) MRI–derived specific ventilation is responsive to
bronchodilator (BD) therapy and associated with clinical biomarkers of type 2 airway inflammation …