Oxidized low density lipoprotein (LDL) is a key factor in the pathogenesis of atherosclerosis
and its thrombotic complications, such as stroke and myocardial infarction. It activates …

Ordered lipid domains enriched in sphingolipids and cholesterol (lipid rafts) have been
implicated in numerous functions in biological membranes. We recently found that lipid domain/…

Revised Manuscript Received May 9, 1995® abstract: The inhA gene has been recently
shownto encode a common protein target for isoniazid and ethionamide action in …

Lipid antigens trigger help from natural killer T cells (NKT cells) for B cells, and direct
conjugation of lipid agonists to antigen profoundly augments antibody responses. Here we show …

Enoyl-ACP reductases participate in fatty acid biosynthesis by utilizing NADH to reduce the
transdouble bond between positions C2 and C3 of a fatty acyl chain linked to the acyl carrier …

Reverse cholesterol transport (RCT) refers to the mobilization of cholesterol on HDL particles
(HDL-C) from extravascular tissues to plasma, ultimately for fecal excretion. Little is known …

The increased use of inhaled nicotine via e-cigarettes has unknown risks to lung health.
Having previously shown that cigarette smoke (CS) extract disrupts the lung microvasculature …

We studied the endocytosis of fluorescent glycosphingolipid (GSL) analogs in various cell
types using pathway-specific inhibitors and colocalization studies with endocytic markers and …

Analysis of sterol distribution and transport in living cells has been hampered by the lack of
bright, photostable fluorescent sterol derivatives that closely resemble cholesterol. In this …

The success of tyrosine kinase inhibitors (TKIs) in treating chronic myeloid leukemia (CML)
depends on the requirement for BCR-ABL1 kinase activity in CML progenitors. However, …