PAD4 deficiency improves bleomycin-induced neutrophil extracellular traps and fibrosis in mouse lung

M Suzuki, J Ikari, R Anazawa, N Tanaka… - American journal of …, 2020 - atsjournals.org
Excessive release of neutrophil extracellular traps (NETs) has been implicated in several
organ fibrosis, including pulmonary fibrosis. NETs constitute a phenomenon in which …

Long-term outcome of chronic thromboembolic pulmonary hypertension at a single Japanese pulmonary endarterectomy center

H Miwa, N Tanabe, T Jujo, F Kato, R Anazawa… - Circulation …, 2018 - jstage.jst.go.jp
Background: Several new treatments for chronic thromboembolic pulmonary hypertension (CTEPH)
have appeared in recent years, which have led to changes in the treatment algorithm…

[HTML][HTML] Longitudinal changes in structural lung abnormalities using MDCT in chronic obstructive pulmonary disease with asthma-like features

R Anazawa, N Kawata, Y Matsuura, J Ikari, Y Tada… - Plos one, 2019 - journals.plos.org
Background Some patients with chronic obstructive pulmonary disease (COPD) have
asthma-like features. However, there have been few reports on the structural lung abnormalities …

Comprehensive lipid profiling of bleomycin‐induced lung injury

…, J Ikari, M Suzuki, R Anazawa… - Journal of Applied …, 2019 - Wiley Online Library
Drug‐induced lung injury is an adverse effect of drug treatment that can result in respiratory
failure. Because lipid profiling could provide cutting‐edge understanding of the …

[HTML][HTML] Dynamic quantitative magnetic resonance imaging assessment of areas of the lung during free-breathing of patients with chronic obstructive pulmonary …

…, N Kawata, H Sato, J Ikari, E Suzuki, R Anazawa… - Academic …, 2022 - Elsevier
Rationale and Objectives Changes in the geometry of the chest wall due to lung hyperinflation
occur in COPD. However, the quantitative assessment of impaired lung motions and its …

Features of radiological and physiological findings in pulmonary capillary hemangiomatosis: an updated pooled analysis of confirmed diagnostic cases

R Anazawa, J Terada, S Sakao… - Pulmonary …, 2019 - journals.sagepub.com
Pulmonary capillary hemangiomatosis (PCH) is a very rare and refractory disease characterized
by capillary angioproliferation. The updated classification of pulmonary hypertension …

Prognostic Nutritional Index (PNI) as a Potential Prognostic Tool for Exacerbation of COPD in Elderly Patients

…, A Shimada, H Sato, R Anazawa… - … Journal of Chronic …, 2023 - Taylor & Francis
Purpose In COPD, exacerbation of the disorder causes a deterioration in the quality-of-life
and worsens respiratory dysfunction, leading to a poor prognosis. In recent years, nutritional …

[HTML][HTML] Objective quantitative multidetector computed tomography assessments in patients with combined pulmonary fibrosis with emphysema: Relationship with …

M Suzuki, N Kawata, M Abe, H Yokota, R Anazawa… - PLoS …, 2020 - journals.plos.org
Background Combined pulmonary fibrosis with emphysema (CPFE) is a clinically meaningful
syndrome characterized by coexisting upper-lobe emphysema and lower-lobe interstitial …

S100A12 inhibits fibroblast migration via the receptor for advanced glycation end products and p38 MAPK signaling

N Tanaka, J Ikari, R Anazawa, M Suzuki… - In Vitro Cellular & …, 2019 - Springer
The migration of lung fibroblasts plays a pivotal role in wound repair and fibrotic processes
in the lung. Although the receptor for advanced glycation end products (RAGE) has been …

Pulmonary capillary hemangiomatosis diagnosed by pathology of explanted lungs: a unique etiology serves as a key of clinical diagnosis

H Wada, T Nakajima, H Suzuki, R Anazawa… - General Thoracic and …, 2019 - Springer
A 27-year-old female patient had presented progressing exertional dyspnea due to pulmonary
hypertension. Chest CT revealed diffusely spread patchy ground-glass opacities sparing …