Pulmonary hypoplasia associated with congenital diaphragmatic hernia (CDH) remains a
major therapeutic problem. Moreover, the pathogenesis of pulmonary hypoplasia in case of …

Congenital diaphragmatic hernia (CDH) is a congenital anomaly consisting of a posterolateral
defect in the diaphragm also known as a Bochdalek hernia. It occurs in 1 in 2000 to 3000 …

Congenital diaphragmatic hernia (CDH) occurs in 1 in 3,000 newborns. Mortality and morbidity
are due to the amount of pulmonary hypoplasia (PH), the response on artificial ventilation …

The outcomes of patients diagnosed with congenital diaphragmatic hernia (CDH) have recently
improved. However, mortality and morbidity remain high, and this is primarily caused by …

Objectives To identify antenatal predictors of persistent pulmonary hypertension ( PPH ) and
the need for extracorporeal membrane oxygenation ( ECMO ) in fetuses with congenital …

Methods: We profiled microRNA expression in prenatal human lungs by microarray analysis.
We then validated this signature with real-time quantitative polymerase chain reaction in …

MicroRNAs (miRNAs) are small (∼22 nucleotides), non-coding RNA molecules that regulate
gene expression post-transcriptionally by inhibiting target mRNAs. Research into the roles …

This guideline was developed by the Canadian CDH Collaborative, a panel of specialists
from across Canada with expertise in the fields of maternal-fetal medicine, pediatric surgery, …

Objective: To evaluate fetal survival after tracheal occlusion in fetuses with severe pulmonary
hypoplasia and isolated congenital diaphragmatic hernia (CDH). Background: Despite …

Congenital diaphragmatic hernia (CDH) is a rare birth defect characterized by incomplete
closure of the diaphragm and herniation of fetal abdominal organs into the chest that results in …